Kiselev K V, Shumakova O A, Maniakhin A Iu
Prikl Biokhim Mikrobiol. 2013 Jan-Feb;49(1):61-6. doi: 10.7868/s0555109913010078.
The biosynthesis of resveratrol after the application of a precursor for biosynthesis, i.e., phenylalanine (Phe), has been studied. The application of Phe has been shown to increase significantly the expression of the phenylalanine-ammonia-lyase (PAL) and stilbene synthase (STS) genes and enhance the production of resveratrol by 8.5 times. Data on resveratrol production after the addition of Phe and coumaric acid (CA) were compared with known analogs.
研究了在应用生物合成前体即苯丙氨酸(Phe)后白藜芦醇的生物合成情况。已表明应用Phe可显著增加苯丙氨酸解氨酶(PAL)和芪合酶(STS)基因的表达,并使白藜芦醇的产量提高8.5倍。将添加Phe和香豆酸(CA)后白藜芦醇的产量数据与已知类似物进行了比较。