Scott William W, Koral Korgun, Margraf Linda R, Klesse Laura, Sacco David J, Weprin Bradley E
Department of Neurosurgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8855, USA.
J Neurosurg Pediatr. 2013 Jul;12(1):6-12. doi: 10.3171/2013.3.PEDS12162. Epub 2013 May 10.
Although intracerebral schwannomas are typically regarded as benign intracranial tumors, malignancy and recurrence have been reported among patients harboring such neoplasms. The available literature consists of case reports and small series that present variable characteristics distinguishing these unusual lesions. Little advancement has been made to further the understanding and management of these tumors. The authors present 3 cases from their institution that highlight the difference between typical benign intracerebral schwannomas and histopathological variants that may portend more aggressive behavior. Also provided is a review of the literature in the hope of gaining a better understanding of these rare tumors.
尽管脑内神经鞘瘤通常被视为良性颅内肿瘤,但已有报道称患有此类肿瘤的患者会出现恶性和复发情况。现有文献包括病例报告和小系列研究,这些研究呈现出区分这些不寻常病变的可变特征。在进一步了解和管理这些肿瘤方面进展甚微。作者展示了他们机构的3个病例,突出了典型良性脑内神经鞘瘤与可能预示更具侵袭性的组织病理学变体之间的差异。同时还提供了文献综述,以期更好地了解这些罕见肿瘤。