脑内神经鞘瘤内出现动静脉畸形样血管的组织学证据：一例报告并文献复习
Histologic Evidence for Arteriovenous Malformation-Like Vasculature Occurring within an Intracerebral Schwannoma: A Case Report and Review of the Literature.
作者信息
Wilson Bayard R, Steinberg Jeffrey A, Snyder Vivian, Jiang Michael N, Carter Bob S
机构信息
School of Medicine, University of California at San Diego, San Diego, California, USA.
Department of Neurosurgery, University of California at San Diego, San Diego, California, USA.
出版信息
World Neurosurg. 2016 Aug;92:582.e9-582.e13. doi: 10.1016/j.wneu.2016.05.078. Epub 2016 Jun 3.
BACKGROUND
The phenomenon of intracerebral schwannoma is exceedingly rare, and its etiology still a matter of debate. No documented cases of intracerebral schwannoma containing vascular elements consistent with those of an arteriovenous malformation (AVM) have been reported. We describe such a case here.
CASE DESCRIPTION
A left temporal intraparenchymal lesion was discovered incidentally in a 34-year-old man after he suffered a mild trauma. The lesion was resected and found on histologic examination to be an intracerebral schwannoma with AVM-like vasculature. The patient made a full recovery after resection.
CONCLUSIONS
To our knowledge, this is the first case of an intracerebral schwannoma with AVM-like characteristics to be reported in the literature. We hypothesize that the co-occurrence of this rare pathologic entity is caused by an interrelated etiologic process, with the tumor microenvironment of the schwannoma inciting the development of the vascular malformation.
背景
脑内神经鞘瘤现象极为罕见，其病因仍存在争议。尚无文献报道脑内神经鞘瘤含有与动静脉畸形（AVM）一致的血管成分的病例。我们在此描述这样一例病例。
病例描述
一名34岁男性在遭受轻度创伤后偶然发现左侧颞叶脑实质内病变。该病变被切除，组织学检查发现是具有AVM样脉管系统的脑内神经鞘瘤。患者切除术后完全康复。
结论
据我们所知，这是文献中首次报道的具有AVM样特征的脑内神经鞘瘤病例。我们推测这种罕见病理实体的共存是由一个相互关联的病因过程引起的，神经鞘瘤的肿瘤微环境促使血管畸形的发展。
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