阿德福韦引起的乙型肝炎患者骨软化症
Osteomalacia induced by adefovir in patient with hepatitis B.
作者信息
Nathali Rivas Zavaleta Mayra, Guayambuco Romero Sonia, Calabozo Raluy Marcelo, Pérez Ruiz Fernando
机构信息
Servicio de Reumatología, Hospital Cruces, Barakaldo, Vizcaya, España.
Servicio de Reumatología, Hospital Cruces, Barakaldo, Vizcaya, España.
出版信息
Reumatol Clin. 2014 Mar-Apr;10(2):120-1. doi: 10.1016/j.reuma.2013.01.006. Epub 2013 May 8.
PMID:23664308
Abstract
Osteomalacia is defined as a defect in mineralization of the bone matrix. We describe the case of a patient with chronic hepatitis B infection in whom treatment with adefovir induced renal phosphate loss with intense and sustained hypophosphatemia which derived in symptomatic osteomalacia.
摘要
骨软化症的定义是骨基质矿化缺陷。我们描述了一例慢性乙型肝炎感染患者的病例，该患者接受阿德福韦治疗后出现肾磷酸盐丢失，并伴有严重且持续的低磷血症，进而导致症状性骨软化症。
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