Kaiser R R, Rückert P R
Pharmazeutisches Institut ETH Zürich, Abt. Galenik.
Klin Monbl Augenheilkd. 1990 May;196(5):405-6. doi: 10.1055/s-2008-1046208.
Good tolerance, long intervals of application and an excellent adhesion are the properties of viscous eye drops (Hydrogels). The use of fusidic acid as a hydrogel in the treatment of bacterial eye infections guarantees a long-lasting antibiotic concentration in tear fluid. When given twice daily, there will be sufficient concentration of the antibiotic in all important tissues of the eye and at the same time it increases the patient compliance.
良好的耐受性、较长的用药间隔时间以及出色的附着力是粘性滴眼液(水凝胶)的特性。使用夫西地酸作为水凝胶治疗细菌性眼部感染可确保泪液中抗生素浓度持久。每日给药两次时,眼部所有重要组织中都会有足够浓度的抗生素,同时还能提高患者的依从性。