Almdahl Sven M, Veel Terje, Halvorsen Per, Rynning Stein E
Department of Cardiac Surgery, Feiring Heart Center, Feiring, Norway.
Interact Cardiovasc Thorac Surg. 2013 Aug;17(2):314-7. doi: 10.1093/icvts/ivt214. Epub 2013 May 10.
Although rare, life-threatening complications requiring emergency cardiac surgery do occur after diagnostic and therapeutic cardiac catheterization procedures. The operative mortality has been persistently reported to remain high. The purpose of this observational study was to evaluate and report the outcomes, with particular emphasis on early mortality, of these risky operations that were performed in a single highly specialized cardiac centre.
Between June 1997 and August 2007, 100 consecutive patients, 13 after diagnostic complicated cardiac catheterization (0.038% of 34,193 angiographies) and 87 after crashed percutaneous coronary intervention (PCI; 0.56% of 15,544 PCIs), received emergency operations at the Feiring Heart Center. In the same period, 10,192 other patients underwent open cardiac surgery. Early outcome data were analysed and compared between the cohorts. Follow-up was 100% complete.
The preoperative status of the 100 patients was that 4 had ongoing external cardiac massage, 24 were in cardiogenic shock, 32 had frank enduring ST-segment infarction but without shock and 40 had threatened acute myocardial infarction. There was 1% (1 patient) 30-day mortality in the study group, which is equal (0.9%, P=0.60) to that of all other operations. Postoperative myocardial infarction and prolonged ventilator use were significantly higher in the crash group, whereas the rate of stroke, renal failure, reopening for bleeding and mediastinitis were similar between the groups.
With rapid transfer to an operation room, minimizing the time of warm myocardial ischaemia, and by performing complete coronary revascularization, it is possible to obtain equally low operative mortality in patients with life-threatening cardiac catheterization-associated complications, as is the case with open cardiac operations in general.
尽管罕见,但在诊断性和治疗性心脏导管插入术之后确实会出现需要紧急心脏手术的危及生命的并发症。一直有报道称手术死亡率居高不下。这项观察性研究的目的是评估并报告在一个高度专业化的心脏中心进行的这些高风险手术的结果,尤其着重于早期死亡率。
在1997年6月至2007年8月期间,费林心脏中心对100例连续患者进行了急诊手术,其中13例在诊断性复杂心脏导管插入术后(占34193例血管造影术的0.038%),87例在急诊经皮冠状动脉介入治疗(PCI)后(占15544例PCI的0.56%)。同期,另有10192例患者接受了心脏直视手术。对各队列的早期结果数据进行了分析和比较。随访完成率为100%。
100例患者的术前状况为:4例正在进行体外心脏按压,24例处于心源性休克,32例有明显的持续性ST段梗死但无休克,40例有急性心肌梗死风险。研究组的30天死亡率为1%(1例患者),与所有其他手术的死亡率相同(0.9%,P = 0.60)。急诊组术后心肌梗死和呼吸机使用时间延长的发生率显著更高,而两组之间的中风、肾衰竭、因出血再次手术和纵隔炎发生率相似。
通过迅速转运至手术室、尽量缩短温暖心肌缺血时间以及进行完全的冠状动脉血运重建,对于伴有危及生命的心脏导管插入术相关并发症的患者,有可能获得与一般心脏直视手术同样低的手术死亡率。