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1994 - 2003年经皮冠状动脉介入治疗后急诊冠状动脉旁路移植术的趋势

Trends in emergency coronary artery bypass grafting after percutaneous coronary intervention, 1994-2003.

作者信息

Haan Constance K, O'Brien Sean, Edwards Fred H, Peterson Eric D, Ferguson T Bruce

机构信息

Division of Cardiothoracic Surgery, University of Florida/Jacksonville, Jacksonville, Florida, USA.

出版信息

Ann Thorac Surg. 2006 May;81(5):1658-65. doi: 10.1016/j.athoracsur.2005.09.079.

DOI:10.1016/j.athoracsur.2005.09.079
PMID:16631652
Abstract

BACKGROUND

In the last decade, percutaneous coronary intervention (PCI) has undergone profound changes in techniques used to achieve revascularization and in patient selection. We examine trends in emergency surgical revascularization after PCI.

METHODS

Using The Society of Thoracic Surgeons National Cardiac Surgery Database, we examined patients undergoing coronary artery bypass grafting within 6 hours of PCI from 1994 to 2003. Stratifying into groups of patients who had and had not suffered myocardial infarction within 24 hours of PCI followed by coronary artery bypass grafting (CABG), we tracked trends in characteristics, predicted risk, and clinical outcomes.

RESULTS

The proportion of isolated CABG procedures done emergently after PCI decreased over 1994 to 1999 from 3,357 of 115,679 (2.9%) to 1,227 of 155,831 (0.8%), remaining stable through 2003. Those suffering myocardial infarction within 24 hours made up a constant proportion of isolated CABG as emergency after PCI (3,352 of 1,042,864; 0.3%) since 1997. Over the decade, the preoperative risk profile worsened, including more elderly patients and more with cerebrovascular disease and congestive heart failure. Operative mortality among these patients has risen with time (from 8.0% to 9.3%; p < 0.0001 for trend), particularly in the setting of acute myocardial infarction (from 14.1% to 16.6%; p < 0.0001 for trend). Similarly, postoperative complications have increased over time, most notably seen in the need for reoperation (10.62% to 24.56%), prolonged postoperative ventilation (25.65% to 54.58%), and renal failure (10.22% to 18.55%).

CONCLUSIONS

In 2005, there remains a low but real need for emergent CABG after PCI, in which operative outcomes are less than ideal, especially in the postinfarction patient, representing an area for cross-specialty collaboration.

摘要

背景

在过去十年中,经皮冠状动脉介入治疗(PCI)在实现血管重建的技术以及患者选择方面发生了深刻变化。我们研究了PCI术后急诊外科血管重建的趋势。

方法

利用胸外科医师协会国家心脏手术数据库,我们研究了1994年至2003年间在PCI术后6小时内接受冠状动脉旁路移植术(CABG)的患者。将患者分为在PCI后24小时内发生心肌梗死并随后接受冠状动脉旁路移植术(CABG)的患者组和未发生心肌梗死的患者组,我们跟踪了患者特征、预测风险和临床结果的趋势。

结果

PCI术后急诊进行的单纯CABG手术比例在1994年至1999年间从115,679例中的3,357例(2.9%)降至155,831例中的1,227例(0.8%),到2003年保持稳定。自1997年以来,在PCI后24小时内发生心肌梗死的患者在单纯CABG急诊手术中所占比例保持恒定(1,042,864例中的3,352例;0.3%)。在这十年间,术前风险状况恶化,包括更多老年患者以及更多患有脑血管疾病和充血性心力衰竭的患者。这些患者的手术死亡率随时间上升(从8.0%升至9.3%;趋势p<0.0001),尤其是在急性心肌梗死的情况下(从14.1%升至16.6%;趋势p<0.0001)。同样,术后并发症随时间增加,最明显的是再次手术需求(10.62%至24.56%)、术后长时间通气(25.65%至54.58%)和肾衰竭(10.22%至18.55%)。

结论

2005年,PCI术后仍存在对急诊CABG的低但实际的需求,其手术结果并不理想,尤其是在心肌梗死后患者中,这代表了一个跨专业合作的领域。

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