Löndahl Magnus
Lund University, Lund, Sweden.
Int J Low Extrem Wounds. 2013 Jun;12(2):152-7. doi: 10.1177/1534734613486154. Epub 2013 May 9.
Hyperbaric oxygen therapy (HBOT) has been suggested to improve healing of hard-to-heal diabetic foot ulcers. Although the wide use of HBOT as a treatment for diabetic foot ulcers has been founded on weak scientific ground, 2 well-designed randomized, double-blind, placebo-controlled studies have in recent years put HBOT on firmer ground as treatment for diabetic patients with chronic foot ulcers. The recognition of inclusion criteria in these studies may help identify a select group of diabetic patients with hard-to-heal ulcers who might benefit from HBOT. In this review, we discuss the rationale behind the use of HBOT, its clinical application, and possible treatment complications.
高压氧疗法(HBOT)已被建议用于改善难愈合的糖尿病足溃疡的愈合情况。尽管将HBOT广泛用作糖尿病足溃疡的治疗方法的科学依据尚不充分,但近年来有两项设计良好的随机、双盲、安慰剂对照研究使HBOT作为慢性足溃疡糖尿病患者的治疗方法有了更坚实的基础。认识这些研究中的纳入标准可能有助于识别出一组可能从HBOT中获益的患有难愈合溃疡的糖尿病患者。在本综述中,我们讨论了使用HBOT的理论依据、其临床应用以及可能的治疗并发症。