类风湿关节炎的喉部受累。
Laryngeal involvement in rheumatoid arthritis.
机构信息
UFSC, Brazil.
出版信息
Braz J Otorhinolaryngol. 2013 Mar-Apr;79(2):233-8. doi: 10.5935/1808-8694.20130040.
UNLABELLED
The prevalence of laryngeal involvement in Rheumatoid Arthritis (RA) ranges from 13 to 75%. The specific RA manifestations include the cricoarytenoid arthritis and the presence of rheumatoid nodules in the vocal folds.
OBJECTIVE
The objective of this study is to evaluate the prevalence of dysphonia and laryngeal alterations on videolaryngoscopy in RA patients and their association with disease activity.
METHOD
This is a clinical cross-sectional study that evaluated patients with rheumatoid arthritis as to their disease activity score in 28 joints (DAS-28), laryngeal symptoms, application of a Portuguese version of the Voice Handicap Index and videolaryngoscopy findings, comparing them with a control group.
RESULTS
We evaluated 47 (54%) patients with rheumatoid arthritis and 40 (46%) controls. The prevalence of dysphonia and videolaryngoscopy changes was respectively 12.8% and 72.4% in patients with RA. The mean of DAS-28 was 3.3 ± 1.2; 26 (74.3%) of 35 patients presenting active disease had laryngeal changes (p = 0.713). Posterior laryngitis was the most common diagnosis (44.7%).
CONCLUSION
The prevalence of laryngeal disorders in RA patients was 72.4% and the prevalence of dysphonia was 12.8%. There was no significant relationship between laryngeal disorders and disease activity.
未注明
类风湿关节炎（RA）患者的喉部受累患病率为 13%至 75%。RA 的具体表现包括环杓关节炎和声带类风湿结节。
目的
本研究旨在评估 RA 患者的嗓音障碍和喉内窥镜改变的患病率及其与疾病活动度的关系。
方法
这是一项临床横断面研究，评估了 28 个关节疾病活动评分（DAS-28）、喉部症状、葡萄牙语嗓音障碍指数（VHI）评分和喉内窥镜检查结果的类风湿关节炎患者，并与对照组进行比较。
结果
我们评估了 47 例（54%）类风湿关节炎患者和 40 例（46%）对照组。RA 患者的声嘶和喉内窥镜改变的患病率分别为 12.8%和 72.4%。DAS-28 的平均值为 3.3 ± 1.2；35 例活动期疾病患者中有 26 例（74.3%）存在喉改变（p = 0.713）。后喉炎是最常见的诊断（44.7%）。
结论
RA 患者的喉部疾病患病率为 72.4%，声嘶的患病率为 12.8%。喉部疾病与疾病活动度之间无显著关系。
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