The University of Edinburgh, Department of Orthopaedics and Trauma, Little France, Old Dalkeith Road, Edinburgh EH16 4SU, UK.
Bone Joint Res. 2013 May 1;2(5):79-83. doi: 10.1302/2046-3758.25.2000150. Print 2013.
Because of the contradictory body of evidence related to the potential benefits of helical blades in trochanteric fracture fixation, we studied the effect of bone compaction resulting from the insertion of a proximal femoral nail anti-rotation (PFNA).
We developed a subject-specific computational model of a trochanteric fracture (31-A2 in the AO classification) with lack of medial support and varied the bone density to account for variability in bone properties among hip fracture patients.
We show that for a bone density corresponding to 100% of the bone density of the cadaveric femur, there does not seem to be any advantage in using a PFNA with respect to the risk of blade cut-out. On the other hand, in a more osteoporotic femoral head characterised by a density corresponding to 75% of the initial bone density, local bone compaction around the helical blade provides additional bone purchase, thereby decreasing the risk of cut-out, as quantified by the volume of bone susceptible to yielding.
Our findings indicate benefits of using a PFNA over an intramedullary nail with a conventional lag screw and suggest that any clinical trial reporting surgical outcomes regarding the use of helical blades should include a measure of the femoral head bone density as a covariable.
由于有关螺旋刀片在转子间骨折固定潜在益处的证据相互矛盾,我们研究了股骨近端防旋髓内钉(PFNA)插入引起的骨压实对骨折固定的影响。
我们针对缺乏内侧支撑的转子间骨折(AO 分类中的 31-A2)开发了一个特定于个体的计算模型,并改变了骨密度,以考虑髋部骨折患者的骨特性变异性。
我们表明,对于与尸体股骨骨密度 100%对应的骨密度,使用 PFNA 似乎并没有任何优势,因为它不会增加刀片切出的风险。另一方面,在更具骨质疏松性的股骨头中,其骨密度对应于初始骨密度的 75%,螺旋刀片周围的局部骨压实提供了额外的骨质固定,从而降低了刀片切出的风险,这可以通过易发生屈服的骨量来量化。
我们的研究结果表明,与使用带有传统拉力螺钉的髓内钉相比,使用 PFNA 具有优势,并表明任何报告有关螺旋刀片使用的手术结果的临床试验都应将股骨头骨密度作为协变量进行测量。