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[东德的肺结核复发——一项1984 - 1986年的社区相关回顾性分析]

[Tuberculosis relapses in East Germany--a community related retrograde analysis 1984-1986].

作者信息

Scharkoff H, Pohl S

机构信息

Bezirksstelle für Lungenkrankheiten und Tuberkulose Cottbus.

出版信息

Pneumologie. 1990 Feb;44 Suppl 1:449-50.

PMID:2367433
Abstract

Basing on a retrospective analysis of 169 cases of relapses of tuberculosis that had been confirmed by bacteriological examinations, we explored possible causes and/or factors favouring a relapse. 6.5% of the mycobacteria cultivated when the relapse was discovered, were resistant to one antibiotic, and 5.3% to two ore more antibiotics. On treating the previous disease, side effects were seen in 31.6%, in 22.3% chemotherapy of the previous disease had been insufficient in respect of duration and/or continuity and/or combination, and in 22.5% the intake of drugs had lacked controlled supervision. In 56% of the relapses there were concomitant diseases (alcoholism in 24.5%, silicosis in 14.9%, diabetes mellitus in 9.7% and gastrointestinal diseases in 5.2%).

摘要

基于对169例经细菌学检查确诊的结核病复发病例的回顾性分析,我们探究了复发的可能原因和/或促成因素。复发时培养出的分枝杆菌中,6.5%对一种抗生素耐药,5.3%对两种或更多种抗生素耐药。在治疗先前疾病时,31.6%出现了副作用,22.3%的先前疾病化疗在疗程和/或连续性和/或联合用药方面不足,22.5%的药物摄入缺乏监控。56%的复发病例伴有其他疾病(酗酒占24.5%,矽肺占14.9%,糖尿病占9.7%,胃肠道疾病占5.2%)。

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