Scharkoff H, Pohl S
Bezirksstelle für Lungenkrankheiten und Tuberkulose Cottbus.
Pneumologie. 1990 Feb;44 Suppl 1:449-50.
Basing on a retrospective analysis of 169 cases of relapses of tuberculosis that had been confirmed by bacteriological examinations, we explored possible causes and/or factors favouring a relapse. 6.5% of the mycobacteria cultivated when the relapse was discovered, were resistant to one antibiotic, and 5.3% to two ore more antibiotics. On treating the previous disease, side effects were seen in 31.6%, in 22.3% chemotherapy of the previous disease had been insufficient in respect of duration and/or continuity and/or combination, and in 22.5% the intake of drugs had lacked controlled supervision. In 56% of the relapses there were concomitant diseases (alcoholism in 24.5%, silicosis in 14.9%, diabetes mellitus in 9.7% and gastrointestinal diseases in 5.2%).
基于对169例经细菌学检查确诊的结核病复发病例的回顾性分析，我们探究了复发的可能原因和/或促成因素。复发时培养出的分枝杆菌中，6.5%对一种抗生素耐药，5.3%对两种或更多种抗生素耐药。在治疗先前疾病时，31.6%出现了副作用，22.3%的先前疾病化疗在疗程和/或连续性和/或联合用药方面不足，22.5%的药物摄入缺乏监控。56%的复发病例伴有其他疾病（酗酒占24.5%，矽肺占14.9%，糖尿病占9.7%，胃肠道疾病占5.2%）。
