Pohl S, Scharkoff H
Bezirksstelle für Lungenkrankheiten und Tuberkulose, Berlin.
Z Erkr Atmungsorgane. 1989;173(1):68-74.
In a cooperative study 169 bacteriologically confirmed tuberculosis relapses of the years 1984-1986 were analysed with regard of causes or relapse favouring factors. In 58.5% relapse occurred 3 or more years after cessation of previous treatment. Relapse was presumedly caused in 22.3% by inadequate chemotherapy (considering duration and/or continuation and/or combination), in 25% by alcoholism and in 14.9% by silicosis. Resistance to 2 or more antituberculotic drugs was found only in 5.3%. Advanced age and polymorbidity are relapse favouring factors. Consideration of adequate chemotherapy is the most important factor to avoid relapse.
在一项合作研究中，对1984年至1986年间169例经细菌学确诊的结核病复发病例进行了病因或复发促进因素分析。58.5%的复发发生在前次治疗停止3年或更长时间之后。据推测，22.3%的复发是由于化疗不足（考虑疗程和/或连续性和/或联合用药），25%是由于酗酒，14.9%是由于矽肺。仅5.3%的病例发现对两种或更多种抗结核药物耐药。高龄和多种疾病并存是复发的促进因素。考虑充分化疗是避免复发的最重要因素。
