Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
BMJ Open. 2013 May 14;3(5):e002970. doi: 10.1136/bmjopen-2013-002970.
Knowledge translation (KT also known as research utilisation, translational medicine and implementation science) is a dynamic and iterative process that includes the synthesis, dissemination, exchange and ethically sound application of knowledge to improve health. After the implementation of KT interventions, their impact on relevant outcomes should be monitored. The objectives of this scoping review are to: (1) conduct a systematic search of the literature to identify the impact on healthcare outcomes beyond 1 year, or beyond the termination of funding of the initiative of KT interventions targeting chronic disease management for end-users including patients, clinicians, public health officials, health services managers and policy-makers; (2) identify factors that influence sustainability of effective KT interventions; (3) identify how sustained change from KT interventions should be measured; and (4) develop a framework for assessing sustainability of KT interventions.
Comprehensive searches of relevant electronic databases (eg, MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials), websites of funding agencies and websites of healthcare provider organisations will be conducted to identify relevant material. We will include experimental, quasi-experimental and observational studies providing information on the sustainability of KT interventions targeting chronic disease management in adults and focusing on end-users including patients, clinicians, public health officials, health services managers and policy-makers. Two reviewers will pilot-test the screening criteria and data abstraction form. They will then screen all citations, full articles and abstract data in duplicate independently. The results of the scoping review will be synthesised descriptively and used to develop a framework to assess the sustainability of KT interventions.
Our results will help inform end-users (ie, patients, clinicians, public health officials, health services managers and policy-makers) regarding the sustainability of KT interventions. Our dissemination plan includes publications, presentations, website posting and a stakeholder meeting.
知识转化（KT，也称为研究利用、转化医学和实施科学）是一个动态和迭代的过程，包括综合、传播、交流和合理应用知识，以改善健康。在实施 KT 干预措施后，应监测其对相关结果的影响。本范围综述的目的是：(1)系统搜索文献，以确定针对慢性病管理的 KT 干预措施对终端用户（包括患者、临床医生、公共卫生官员、卫生服务管理人员和政策制定者）的影响是否超过 1 年，或超过倡议资金的终止；(2)确定影响有效 KT 干预措施可持续性的因素；(3)确定如何衡量 KT 干预措施的持续变化；(4)制定评估 KT 干预措施可持续性的框架。
将全面搜索相关电子数据库（例如，MEDLINE、EMBASE、Cochrane 对照试验中心注册）、资助机构网站和医疗机构组织网站，以确定相关材料。我们将包括针对成年人慢性病管理的 KT 干预措施的可持续性的实验、准实验和观察性研究，重点关注终端用户，包括患者、临床医生、公共卫生官员、卫生服务管理人员和政策制定者。两名审查员将对筛选标准和数据提取表进行试点测试。然后，他们将独立地对所有引文、全文和摘要数据进行双重筛选。范围综述的结果将进行描述性综合，并用于开发评估 KT 干预措施可持续性的框架。
我们的研究结果将帮助终端用户（即患者、临床医生、公共卫生官员、卫生服务管理人员和政策制定者）了解 KT 干预措施的可持续性。我们的传播计划包括出版物、演讲、网站发布和利益相关者会议。
