von Eiff M, Roos N, Glaser J, Baumgart P, Walger P, Steimann R
Medizinische Klinik A der Universität Münster.
Pneumologie. 1990 Feb;44 Suppl 1:548-9.
In 73 patients with pneumonia treated empirically with antibiotics or antimycotics, a bronchoscopy with bronchoalveolar lavage was performed in an attempt to identify the pathogens involved. Patients in whom it proved possible to detect a specific pathogen showed a lower mortality rate than did those in whom it was not possible to clarify the aetiology of the pneumonia (24 per cent and 34 per cent, respectively). In patients receiving empirical treatment over a long term, pneumonia persisted longer, and the mortality rate was higher, than in patients who were submitted to invasive examination early on.
在73例接受抗生素或抗真菌药物经验性治疗的肺炎患者中,进行了支气管镜检查及支气管肺泡灌洗,以试图确定相关病原体。能够检测到特定病原体的患者死亡率低于无法明确肺炎病因的患者(分别为24%和34%)。与早期接受侵入性检查的患者相比,长期接受经验性治疗的患者肺炎持续时间更长,死亡率更高。