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釉基质蛋白衍生物:在牙周组织再生中的作用

Enamel matrix protein derivatives: role in periodontal regeneration.

作者信息

Rathva Vandana J

机构信息

Department of Periodontics, KM Shah Dental College and Hospital, Sumandeep University, Gujarat, India.

出版信息

Clin Cosmet Investig Dent. 2011 Dec 1;3:79-92. doi: 10.2147/CCIDEN.S25347. Print 2011.

Abstract

The role of regenerative periodontal therapy is the reconstitution of lost periodontal structures, ie, new formation of root cementum, periodontal ligament, and alveolar bone. The outcome of basic research has pointed to the important role of enamel matrix protein derivative (EMD) in periodontal wound healing. Histologic results from animal and human studies have shown that treatment with EMD promotes periodontal regeneration. Moreover, clinical studies have indicated that treatment with EMD positively influences periodontal wound healing in humans. The goal of this paper is to review the existing literature on EMD.

摘要

再生性牙周治疗的作用是重建缺失的牙周结构,即牙根牙骨质、牙周膜和牙槽骨的新形成。基础研究结果表明釉基质蛋白衍生物(EMD)在牙周伤口愈合中具有重要作用。动物和人体研究的组织学结果显示,EMD治疗可促进牙周再生。此外,临床研究表明,EMD治疗对人类牙周伤口愈合有积极影响。本文的目的是综述关于EMD的现有文献。

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