Abubakar S A, Isezuo S A
Department of medicine Ahmadu Bello University Teaching Hospital, Zaria, Nigeria;
Int J Biomed Sci. 2012 Sep;8(3):183-7.
Stroke has a major impact on survivors including Health related Quality of life (HRQoL). HRQoL measurements are potentially more relevant to patients than measurements of impairments or disability and are an important index of outcome after stroke that can facilitate a broader description of disease and outcome. This study examined the factors associated with HRQoL of stroke survivors.
In a cross-sectional and descriptive correlational design, 62 patients were prospectively enrolled and interviewed 3 months post stroke in neurology out-patient clinic. After case identification, functional status (handicap) was determined using the Modified Rankin Scale (MRS), while Zung Depression Self-Rating Scale (ZDS) was used to determine presence of depression. HRQoL was assessed using the Stroke Impact Scale-16 (SIS-16). Age, sex, duration of formal education, depression and degree of disability were correlated with HRQoL in multiple logistic regressions.
The mean age of patients was 54.4 ± 9.9 years. Mean duration of formal education was significantly higher in males than females (p value=0.007). About one third (29%) of the stroke survivors were depressed and more than half (54.8%) had good recovery. Function status measured by modified Rankin Scale and depression were independent determinants of poor HRQoL.
Functional status and depression were identified as independent factors affecting HRQoL of stroke survivors.
中风对幸存者有重大影响，包括与健康相关的生活质量（HRQoL）。HRQoL测量对患者而言可能比损伤或残疾测量更具相关性，并且是中风后结局的重要指标，可促进对疾病和结局更广泛的描述。本研究探讨了与中风幸存者HRQoL相关的因素。
采用横断面描述性相关设计，前瞻性纳入62例患者，并于中风后3个月在神经内科门诊进行访谈。在确定病例后，使用改良Rankin量表（MRS）确定功能状态（残疾程度），同时使用Zung抑郁自评量表（ZDS）确定是否存在抑郁。使用中风影响量表-16（SIS-16）评估HRQoL。在多元逻辑回归中，将年龄、性别、正规教育年限、抑郁和残疾程度与HRQoL进行相关性分析。
患者的平均年龄为54.4±9.9岁。男性的平均正规教育年限显著高于女性（p值=0.007）。约三分之一（29%）的中风幸存者存在抑郁，超过一半（54.8%）恢复良好。改良Rankin量表测量的功能状态和抑郁是HRQoL较差的独立决定因素。
功能状态和抑郁被确定为影响中风幸存者HRQoL的独立因素。
