Allen B, Loflin T G, Embry B M, Gaskin T A, Isobe J H, Martin R G
Department of Radiology, Baptist Medical Center Hospitals, Birmingham, Alabama.
Radiology. 1990 Aug;176(2):543-7. doi: 10.1148/radiology.176.2.2367673.
Optically diverged direct argon laser light energy was used prior to conventional balloon angioplasty to recanalize 30 occluded peripheral arteries in 26 patients. Three of five (60%) iliac and 22 of 25 (88%) femoropopliteal lesions ranging in length from 1 to 47 cm (mean, 17.3 cm) were successfully treated, for an overall technical success rate of 83%. In the femoropopliteal system, 13 of 14 (93%) procedures in lesions less than 20 cm and nine of 11 (82%) procedures in lesions greater than 20 cm were treated successfully. No statistically significant differences in success rate based on lesion site, lesion length, degree of lesion calcification, or severity of peripheral vascular disease were found. Major complications were a laser perforation resulting in treatment failure in one case (3%) and a successfully treated distal embolus in another (3%). No reocclusions occurred in the immediate postoperative period. While long-term follow-up will be required to assess continued patency, this system can potentially increase the number of patients amenable to conventional balloon angioplasty and is currently advocated as an alternative to amputation in patients in whom surgical bypass grafting is contraindicated or unfeasible.
在传统球囊血管成形术之前，使用光学发散的直接氩激光能量对26例患者的30条闭塞性外周动脉进行再通。5条髂动脉病变中的3条（60%）以及25条股腘动脉病变中的22条（88%）成功得到治疗，病变长度从1至47厘米（平均17.3厘米），总体技术成功率为83%。在股腘动脉系统中，病变小于20厘米的14例手术中有13例（93%）成功，病变大于20厘米的11例手术中有9例（82%）成功。未发现基于病变部位、病变长度、病变钙化程度或外周血管疾病严重程度的成功率存在统计学显著差异。主要并发症为1例（3%）激光穿孔导致治疗失败，另1例（3%）成功治疗远端栓子。术后即刻未发生再闭塞。虽然需要长期随访以评估持续通畅情况，但该系统可能会增加适合传统球囊血管成形术的患者数量，目前被提倡作为手术旁路移植术禁忌或不可行患者截肢的替代方法。
