UKCRC Centre of Excellence for Public Health, Queen's University Belfast, Belfast, UK; Cancer Epidemiology and Health Services Research Group, Centre for Public Health, Queen's University Belfast, Belfast, UK.
Psychooncology. 2013 Nov;22(11):2428-35. doi: 10.1002/pon.3304. Epub 2013 May 16.
Cancer survivors (CSs) are at risk of developing late effects (LEs) associated with the disease and its treatment. This paper compares the health status, care needs and use of health services by CSs with LEs and CSs without LEs.
Cancer survivors (n = 613) were identified via the Northern Ireland Cancer Registry and invited to participate in a postal survey that was administered by their general practitioner. The survey assessed self-reported LEs, health status, health service use and unmet care needs. A total of 289 (47%) CSs responded to the survey, and 93% of respondents completed a LEs scale.
Forty-one per cent (111/269) of CSs reported LEs. Survivors without LEs and survivors with LEs were comparable in terms of age and gender. The LEs group reported a significantly greater number of co-morbidities, lower physical health and mental health scores, greater overall health service use and more unmet needs. Unadjusted logistic regression analysis found that cancer site, time since diagnosis and treatment were significantly associated with reporting of LEs. CSs who received combination therapies compared with CSs who received single treatments were over two and a half times more likely to report LEs (OR = 2.63, 95% CI = 1.32-5.25) after controlling for all other variables.
The CS population with LEs comprises a particularly vulnerable group of survivors who have multiple health care problems and needs and who require tailored care plans that take account of LEs and their impact on health-related quality of life.
癌症幸存者（CSs）面临与疾病及其治疗相关的晚期效应（LEs）的风险。本文比较了有 LEs 的 CSs 和无 LEs 的 CSs 的健康状况、护理需求和卫生服务利用情况。
通过北爱尔兰癌症登记处确定癌症幸存者（n = 613），并邀请他们的全科医生参与邮寄调查。该调查评估了自我报告的 LEs、健康状况、卫生服务利用情况和未满足的护理需求。共有 289 名（47%）CSs 对调查做出了回应，93%的受访者完成了 LEs 量表。
41%（111/269）的 CSs 报告了 LEs。无 LEs 的幸存者和有 LEs 的幸存者在年龄和性别方面具有可比性。LEs 组报告了更多的合并症、较低的身体和心理健康评分、更多的整体卫生服务利用和更多的未满足需求。未调整的逻辑回归分析发现，癌症部位、诊断后时间和治疗与 LEs 的报告显著相关。与接受单一治疗的 CSs 相比，接受联合治疗的 CSs 报告 LEs 的可能性高出 2.5 倍以上（OR = 2.63，95% CI = 1.32-5.25），在控制所有其他变量后。
有 LEs 的 CSs 人群是一个特别脆弱的幸存者群体，他们有多种健康问题和需求，需要制定专门的护理计划，考虑到 LEs 及其对健康相关生活质量的影响。
