Department of Pediatric Surgery, Erasmus MC - Sophia Children's Hospital, 3000 CB Rotterdam, the Netherlands.
Dis Esophagus. 2013 May-Jun;26(4):417-21. doi: 10.1111/dote.12059.
Survival rates in esophageal atresia (EA) patients have reached 90%. In long-term follow-up studies the focus has shifted from purely surgical or gastrointestinal evaluation to a multidisciplinary approach. We evaluated the long-term morbidity in adolescent and adult EA patients and discussed mainly nonsurgical issues. Dysphagia is common and reported in up to 85% of patients. In young adults gastroesophageal reflux disease occurs frequently with development of Barrett esophagus in 6% reported in different series. It is difficult to estimate respiratory morbidity from the literature because many different definitions, questionnaires, and study designs have been used. However, many patients seem to suffer from respiratory problems even into adulthood. In conclusion, morbidity is not only restricted to surgical problems but many different domains are involved. These are all related and together determine to a large extent the quality of life of EA patients and also of their families. We assume that a multidisciplinary care approach seems best to address their special needs.
食管闭锁（EA）患者的存活率已达到 90%。在长期随访研究中，重点已从单纯的手术或胃肠道评估转移到多学科方法。我们评估了青少年和成年 EA 患者的长期发病率，并主要讨论了非手术问题。吞咽困难很常见，高达 85%的患者有此报告。在年轻成年人中，胃食管反流病很常见，不同系列报道中，6%的患者发展为巴雷特食管。由于文献中使用了许多不同的定义、问卷和研究设计，因此很难估计呼吸系统发病率。然而，许多患者即使在成年后也似乎存在呼吸问题。总之，发病率不仅限于手术问题，许多不同的领域都涉及到。这些都是相互关联的，它们共同在很大程度上决定了 EA 患者及其家庭的生活质量。我们假设多学科护理方法似乎是解决他们特殊需求的最佳方法。
