Department of Dermatology, Lady Hardinge Medical College & Assoc. Hospitals, New Delhi, India.
Int J Dermatol. 2013 Jun;52(6):750-2. doi: 10.1111/j.1365-4632.2012.05752.x.
Airway hemangiomas can be difficult to manage and cause anxiety in both the parents and the treating physician. Propranolol, a nonselective beta-blocker, has recently been used for treating proliferating infantile hemangiomas. We report successful management of a proliferating, large, mixed infantile hemangioma with subglottic extension in an Indian infant using oral propranolol in a dose of 2mg/kg/day without any side effects. Induction of early involution and freedom from the side effects of steroid therapy seem encouraging for using propranolol as a first line treatment modality in the management of troublesome hemangiomas.
气道血管瘤的管理颇具难度,会令患儿父母和治疗医生都感到焦虑。普萘洛尔是一种非选择性β受体阻滞剂,最近已被用于治疗增殖性婴儿血管瘤。我们报告了一例印度婴儿,患有增殖性、大型、混合性伴声门下延伸的婴儿血管瘤,使用 2mg/kg/天的口服普萘洛尔剂量进行治疗,取得了成功,且无任何副作用。早期消退和避免类固醇治疗的副作用似乎令人鼓舞,可将普萘洛尔作为治疗棘手血管瘤的一线治疗方法。