Nonikov V E, Zubkov M N, Gugutsidze E N
Ter Arkh. 1990;62(3):30-4.
As many as 356 patients afflicted with acute pneumonias (of these, 225 were from 60 to over years of age) underwent examinations according to the program including bacteriological analysis of the mucus and detection of antigens and specific antibodies in the blood serum. The etiology of acute pneumonia was established in 346 patients (97.2%). In the etiological structure of acute pneumonia, there prevailed bacteria, among which pneumococci, streptococci and hemophilic bacilli occurring both in the form of monocultures and as a constituent part of associations were mostly demonstrable. Acute pneumonias caused by Legionella, Klebsiella and staphylococci were encountered comparatively seldom. The rate of the demonstration of Mycoplasma and viral bacterial associations varied depending on the epidemiological situation. In young persons, acute pneumonias were induced primarily by bacterial monocultures, Mycoplasma, and viral bacterial associations. The latter ones were demonstrated more frequently in persons over 60. The authors review the information content of the employed diagnostic program for the verification of bacterial monocultures and associations of causative agents. Note that penicillin, tetracyclines and biseptol are less effective in respect of bacterial associations detectable in elderly persons.
多达356例急性肺炎患者(其中225例年龄在60岁及以上)按照该方案接受了检查,包括痰液的细菌学分析以及血清中抗原和特异性抗体的检测。346例患者(97.2%)明确了急性肺炎的病因。在急性肺炎的病因构成中,细菌占主导,其中肺炎球菌、链球菌和嗜血杆菌以单一培养形式以及作为菌群组成部分的形式最为常见。由军团菌、克雷伯菌和葡萄球菌引起的急性肺炎相对较少见。支原体和病毒-细菌混合感染的检出率因流行病学情况而异。在年轻人中,急性肺炎主要由细菌单一培养、支原体和病毒-细菌混合感染引起。后者在60岁以上人群中更常见。作者回顾了用于验证细菌单一培养和病原体组合的所用诊断方案的信息内容。注意,青霉素、四环素和复方新诺明对老年人中可检测到的细菌组合效果较差。