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马来西亚精神分裂症患者的功能缓解和就业情况。

Functional remission and employment among patients with schizophrenia in Malaysia.

机构信息

Department of Psychiatry and Mental Health, Hospital Kajang, Selangor, Malaysia.

出版信息

Compr Psychiatry. 2014 Jan;55 Suppl 1:S46-51. doi: 10.1016/j.comppsych.2013.03.007. Epub 2013 May 13.

Abstract

OBJECTIVE

The study aimed to determine the rates of functional remission and employment as well as the factors associated with functional remission among patients with Schizophrenia, receiving community psychiatric service in an urban setting in Malaysia.

METHODS

From a total of 250 patients randomly selected, 155 fulfilled the study requirement and were assessed on their functional remission status using the Personal and Social Performance Scale. The relationships between functional remission and socio-demographic factors, clinical factors, social support, symptom remission and rates of hospitalization were examined.

RESULTS

The results revealed that 74% (n=115) of the respondents had functional remission with only 20% (n=31) currently employed. Functional remission was found to be significantly associated with good social support (84.4% versus 36.4% p<0.001, OR=9.487 [95% CI=4.008-22.457]); shorter illness duration of less than 10 years (81.2% versus 66.7% p=0.038, OR=2.167 [95% CI=1.035-4.535]); good medication compliance (79.1% versus 50.0% p=0.002, OR=3.778 [95% CI=1.570-9.090]); hospital admissions of lower than 3 per year (80.5% versus 44.4% p<0.001 OR=5.150 [95% CI=2.145-12.365]) and; symptomatic remission (87.3% versus 37.4% p<0.001 [95% CI=0.070 (0.029-0.168]). A multiple regression analysis revealed only social support, lower hospitalization rate and symptom remission, as significant predictors of functional remission.

CONCLUSION

A majority of patients with Schizophrenia in this study achieved functional remission, however, only a small percentage of them were employed. Functional remission was influenced by severity of illness and levels of social support in these patients.

摘要

目的

本研究旨在确定在马来西亚城市环境下接受社区精神卫生服务的精神分裂症患者的功能缓解率和就业率,以及与功能缓解相关的因素。

方法

从随机选择的 250 名患者中,共有 155 名患者符合研究要求,并使用个人和社会表现量表评估其功能缓解状态。研究考察了功能缓解与社会人口统计学因素、临床因素、社会支持、症状缓解和住院率之间的关系。

结果

结果显示,74%(n=115)的受访者有功能缓解,仅有 20%(n=31)的人目前有工作。研究发现,功能缓解与良好的社会支持显著相关(84.4%比 36.4%,p<0.001,OR=9.487[95%CI=4.008-22.457]);疾病持续时间少于 10 年(81.2%比 66.7%,p=0.038,OR=2.167[95%CI=1.035-4.535]);良好的药物依从性(79.1%比 50.0%,p=0.002,OR=3.778[95%CI=1.570-9.090]);每年住院次数少于 3 次(80.5%比 44.4%,p<0.001,OR=5.150[95%CI=2.145-12.365]);症状缓解(87.3%比 37.4%,p<0.001[95%CI=0.070(0.029-0.168])。多元回归分析显示,只有社会支持、较低的住院率和症状缓解是功能缓解的显著预测因素。

结论

本研究中大多数精神分裂症患者达到了功能缓解,但只有一小部分人就业。功能缓解受患者病情严重程度和社会支持水平的影响。

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