Yao Lansicheng, Liu Hongying, Pan Qiuyu, Tian Xiaobing
Foreign Affairs Office, North Sichuan Medical College, Nanchong, Sichuan, China.
Department of Psychiatric Rehabilitation, Nanchong Psychosomatic Hospital Affiliated to North Sichuan Medical College, Nanchong, Sichuan, China.
Front Psychiatry. 2024 Jun 27;15:1404059. doi: 10.3389/fpsyt.2024.1404059. eCollection 2024.
Schizophrenia is a severe and enduring psychiatric disorder, characterized by substantial challenges in achieving symptomatic remission. Up to now, there have been limited studies examining the association between remission status and social support in patients with schizophrenia during COVID-19. This study aimed to investigate the remission status of community-dwelling schizophrenia patients during the pandemic and explore whether symptomatic remission is significantly associated with social support in a cross-sectional study.
727 schizophrenia patients were recruited using a cluster random sampling method in the local community. Face-to-face interviews were used to gather data on participants' clinical characteristics, sociodemographic, social support, and symptomatic remission criteria. Logistic regression models were deployed to identify potential relationships between symptomatic remission and social support.
Among the 727 patients in our study, a substantial proportion of 522 (71.80%) achieved symptomatic remission, while 205 (28.2%) did not. Remarkably, those who achieved symptomatic remission exhibited a higher level of social support (28.32 ± 6.82) compared to those who did not. The proportion of patients achieving symptomatic remission in the low (19.4%), medium (46.2%), and high (34.3%) social support groups was 56.7%, 66.1%, and 88.0%, respectively. Moreover, the crude odds ratio for the association between social support and symptomatic remission was 3.20 (95% CI: 2.45-4.18). After controlling for all confounding factors, the adjusted odds ratio remained significant at 3.02 (95% CI: 2.30-3.97).
This consistent association underscores the critical role of social support in influencing symptomatic remission among community-dwelling schizophrenia patients, especially during the COVID-19 pandemic. Reinforcing the utilization of social support for fostering symptomatic remission among individuals with schizophrenia who reside in the community during such crises is recommended.
精神分裂症是一种严重且持久的精神障碍,其特征在于实现症状缓解面临重大挑战。到目前为止,在新冠疫情期间,研究精神分裂症患者缓解状态与社会支持之间关联的研究有限。本研究旨在通过一项横断面研究,调查疫情期间社区居住的精神分裂症患者的缓解状态,并探讨症状缓解是否与社会支持显著相关。
采用整群随机抽样方法在当地社区招募了727名精神分裂症患者。通过面对面访谈收集参与者的临床特征、社会人口统计学、社会支持和症状缓解标准的数据。采用逻辑回归模型来确定症状缓解与社会支持之间的潜在关系。
在我们研究的727名患者中,相当一部分522名(71.80%)实现了症状缓解,而205名(28.2%)未实现。值得注意的是,实现症状缓解的患者比未实现的患者表现出更高水平的社会支持(28.32±6.82)。在低(19.4%)、中(46.2%)、高(34.3%)社会支持组中实现症状缓解的患者比例分别为56.7%、66.1%和88.0%。此外,社会支持与症状缓解之间关联的粗比值比为3.20(95%置信区间:2.45 - 4.18)。在控制所有混杂因素后,调整后的比值比仍显著为3.02(95%置信区间:2.30 - 3.97)。
这种一致的关联强调了社会支持在影响社区居住的精神分裂症患者症状缓解方面的关键作用,尤其是在新冠疫情期间。建议在这种危机期间,加强社会支持的利用,以促进社区居住的精神分裂症患者的症状缓解。