Adedoyin Rufus A, Afolabi Abiodun, Adegoke Olajire O, Akintomide Anthony O, Awotidebe Taofeek O
Department of Medical Rehabilitation, Obafemi Awolowo University, Ile-Ife, Nigeria.
Diabetes Metab Syndr. 2013 Apr-Jun;7(2):91-4. doi: 10.1016/j.dsx.2013.02.014. Epub 2013 Mar 14.
The study determined the diastolic and systolic pressure, anthropometric parameters, serological parameters comprising fasting blood glucose (FBG), triglyceride (TG) and high density lipoprotein cholesterol (HDL-C) as well as the socio-economic status (SES) of inhabitants of Ilora with a view to providing information on impact of SES on metabolic syndrome (MetS). One hundred participants (54 males and 46 females) whose ages ranged from 30 and 70 years, participated in the study. Participants were recruited from the three wards of the town using multi-stage random sampling procedure. Subjects' weights, height, blood pressure, waist circumference (WC) were measured using standard instruments. Fasting blood glucose (FBG) was measured using a glucometer on participants' blood samples taken after at least 8h of fasting. Serum triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C) were analyzed using enzyme colometric assay kits in the laboratory. SES of the participants was determined by using a questionnaire, which sought information on annual income, occupation and education. Participants who had MetS were determined using the new International Diabetes Foundation definition of MetS. Both descriptive and inferential statistics were used to analyze the data. The mean scores for the males and females systolic blood pressure (SBP) were 123.20 ± 20.72 mmHg and 117.78 ± 14.64 mmHg, and the diastolic blood pressure (DBP), 78.63 ± 11.72 mmHg and 75.98 ± 13.06 mmHg, respectively. The mean of serological variables scores for the males and females, respectively, were FBG (4.95 ± 0.81 mmol/L and 4.84 ± 1.36 mmol/L), TG (1.28 ± 0.75 mmol/L and 1.35 ± 1.05 mmol/L), HDL-C (1.26 ± 0.21 mmol/L and 2.32 ± 7.34 mmol/L). The mean SES scores for the males and females were 14.35 ± 4.75 and 13.13 ± 4.66, respectively. The prevalence of MetS was 43.5% in females and 9.3% in males. Significant differences were found in SBP and FBG across the three SES groups (F=3.148 and 3.862, respectively, p<0.05). The high SES group was found to have significantly higher SBP and FBG than the low and middle SES groups. There were significant correlations between SES scores and SBP (r=0.255; p<0.05), FBG (r=0.270; p<0.01), and BMI (r=0.210; p<0.05). Also, significant relationships were found between weight and TG (r=0.282; p<0.05), waist circumference (WC) and FBG (r=0.264; p<0.05), and WC and TG (r=0.414; p<0.01). The study concluded that SES has significant relationship with metabolic syndrome components such as SBP and fasting blood glucose among adult population in Nigeria.
该研究测定了伊洛拉居民的舒张压和收缩压、人体测量参数、包括空腹血糖（FBG）、甘油三酯（TG）和高密度脂蛋白胆固醇（HDL-C）在内的血清学参数以及社会经济地位（SES），旨在提供有关SES对代谢综合征（MetS）影响的信息。100名年龄在30至70岁之间的参与者（54名男性和46名女性）参与了该研究。参与者通过多阶段随机抽样程序从该镇的三个选区招募。使用标准仪器测量受试者的体重、身高、血压、腰围（WC）。在参与者至少禁食8小时后采集的血样上使用血糖仪测量空腹血糖（FBG）。在实验室中使用酶比色测定试剂盒分析血清甘油三酯（TG）和高密度脂蛋白胆固醇（HDL-C）。通过一份问卷确定参与者的SES，该问卷收集有关年收入、职业和教育的信息。使用新的国际糖尿病联盟MetS定义确定患有MetS的参与者。使用描述性和推断性统计分析数据。男性和女性收缩压（SBP）的平均得分分别为123.20±20.72mmHg和117.78±14.64mmHg，舒张压（DBP）分别为78.63±11.72mmHg和75.98±13.06mmHg。男性和女性血清学变量得分的平均值分别为FBG（4.95±0.81mmol/L和4.84±1.36mmol/L）、TG（1.28±0.75mmol/L和1.35±1.05mmol/L）、HDL-C（1.26±0.21mmol/L和2.32±7.34mmol/L）。男性和女性的平均SES得分分别为14.35±4.75和13.13±4.66。MetS的患病率在女性中为43.5%，在男性中为9.3%。在三个SES组中，SBP和FBG存在显著差异（F分别为3.148和3.862，p<0.05）。发现高SES组的SBP和FBG显著高于低SES组和中SES组。SES得分与SBP（r=0.255；p<0.05）、FBG（r=0.270；p<0.01）和BMI（r=0.210；p<0.05）之间存在显著相关性。此外，体重与TG（r=0.282；p<0.05）、腰围（WC）与FBG（r=0.264；p<0.05）以及WC与TG（r=0.414；p<0.01）之间存在显著关系。该研究得出结论，在尼日利亚成年人群中，SES与代谢综合征成分如SBP和空腹血糖之间存在显著关系。
