Department of Health, Generalitat of Catalonia, Spain.
Tuberculosis (Edinb). 2013 Jul;93(4):456-60. doi: 10.1016/j.tube.2013.04.004. Epub 2013 May 13.
Immigrants may not transmit tuberculosis (TB) more than indigenous patients. The objective was to study the prevalence of TB infection among contacts of immigrant and indigenous TB patients and the risk factors associated with latent TB infection.
Contacts of TB cases recorded in 2005 and 2006 were surveyed using a standardized Health Department questionnaire. Infections were diagnosed using the tuberculin skin test (TST) (cut-off ≥ 5 mm). The risk of infection was determined by multivariate logistic regression and the adjusted odds ratios (aOR) with the 95% confidence intervals (CI) were calculated.
The study of contacts was completed in 1329 cases of TB. The prevalence of infection was 32.3% (3038/9406) in all contacts, 41.4% in contacts of immigrant cases and 29.2% in contacts of indigenous cases. In the multivariate analysis, immigrant index cases were not associated with an increased risk (aOR = 0.9; 95%CI: 0.8-1.0). The prevalence of TST conversion was 10.0% (296/2969) in all contacts, 11.2% in immigrant contacts and 9.7% in indigenous contacts (p = 0.158).
Immigrants do not transmit TB more than indigenous TB patients. Infections which may have occurred in the countries of origin of immigrants were detected by the systematic study of contacts.
移民传播结核病（TB）的可能性不比本国土著患者高。本研究旨在调查移民和本国土著结核病患者接触者中 TB 感染的流行率，并分析潜伏性 TB 感染的相关危险因素。
采用标准的卫生部门调查问卷，对 2005 年和 2006 年记录的结核病病例的接触者进行调查。采用结核菌素皮肤试验（TST）（切点≥5mm）诊断感染。采用多变量 logistic 回归分析确定感染风险，并计算调整后的比值比（aOR）及其 95%置信区间（CI）。
完成了对 1329 例结核病病例接触者的研究。在所有接触者中，感染率为 32.3%（3038/9406），移民病例接触者为 41.4%，本国土著病例接触者为 29.2%。多变量分析显示，移民病例并非感染风险增加的危险因素（aOR=0.9；95%CI：0.8-1.0）。在所有接触者中，TST 转化率为 10.0%（296/2969），移民接触者为 11.2%，本国土著接触者为 9.7%（p=0.158）。
移民传播结核病的可能性不比本国土著结核病患者高。通过对接触者进行系统研究，发现了可能在移民原籍国发生的感染。
