Movement Disorders Unit, Neurology Service, Hospital de Clínicas, Federal University of Paraná, Curitiba, PR, Brazil.
Parkinsonism Relat Disord. 2013 Aug;19(8):751-4. doi: 10.1016/j.parkreldis.2013.04.021. Epub 2013 May 14.
Unusual delusional syndromes are rare protean diseases with speculative etiopathogenic mechanisms.
Seven consecutive patients with advanced PD were evaluated over a 15-year period at the Movement Disorders Unit in the Neurology Service, Hospital de Clínicas, Federal University of Paraná, and the Paraná State Parkinson's Patients Association.
We describe advanced Parkinson's disease patients presenting with unusual delusional syndromes, including cases of Ekbom, Othello, Capgras' and Diogenes syndromes, reduplicative paramnesia and mirrored-self misidentification.
There are a few isolated reports of unusual neuropsychiatric disorders in patients with PD. We believe that these syndromes associated with advanced PD in elderly patients presenting with cognitive impairment and polypharmacy are probably often underestimated. Neurologists should be aware for these rare and treatable conditions.
不常见的妄想综合征是罕见的多变性疾病,其发病机制尚不确定。
在 15 年的时间里,我们在神经病学服务部的运动障碍科、联邦大学的 Paraná 医院和 Paraná 州帕金森病患者协会连续评估了 7 名患有晚期 PD 的患者。
我们描述了患有不常见妄想综合征的晚期帕金森病患者,包括 Ekbom、Othello、Capgras 和 Diogenes 综合征、复制性妄想和镜像自我识别病例。
有少数关于 PD 患者出现不常见神经精神障碍的孤立报告。我们认为,这些综合征与认知障碍和多种药物治疗的老年晚期 PD 患者相关,可能经常被低估。神经科医生应该意识到这些罕见且可治疗的疾病。