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[流行性腮腺炎后男性生育力低下时睾丸生殖功能的临床统计学特征]

[The clinico-statistical characteristics of the testicular generative function in male subfertility following mumps].

作者信息

Shakhov E V, Krupin V N

出版信息

Urol Nefrol (Mosk). 1990 Mar-Apr(2):46-50.

PMID:2368216
Abstract

The paper emphasized the role of mumps complicated by orchitis in the etiology of male subfertility with allowances for a possible development of testicular degeneration in the course of epidemic parotiditis alone, i.e. without clinically evident orchitis. To distinguish the impact of mumps sustained in childhood on the infertility development clinical and laboratory investigations would be advisable in the majority of subfertile males. The results of clinical and statistical study of 865 infertile males aged between 20 and 36 yrs whose marital life varied from 8 mos to 12 yrs were reported. Anamnestic evidence of epidemic parotiditis sustained at the age of 5-13 yrs was found in 174 examinees (20.1 per cent). Spermographic data on subfertile males with a history of mumps were exposed to statistical computation and correlated with the data on 200 subfertile males who avoided the disease and the data on 22 healthy fertile males. The authors noted significantly low (p less than 0.05) contents of ejaculate spermatozoa in subfertile males with a history of mumps and a significantly low number of morphologically normal spermatozoa (p less than 0.001) in comparison to those values in subfertile males without a history of epidemic parotiditis.

摘要

该论文强调了腮腺炎并发睾丸炎在男性生育力低下病因中的作用,认为在流行性腮腺炎病程中,即便没有明显的临床睾丸炎表现,也可能发生睾丸变性。对于大多数生育力低下的男性而言,为区分童年时期患腮腺炎对不育症发展的影响,进行临床和实验室检查是可取的。报告了对865名年龄在20至36岁之间、婚姻生活时长从8个月至12年不等的不育男性进行临床和统计研究的结果。在174名受检者(20.1%)中发现有5至13岁时患流行性腮腺炎的既往史。对有腮腺炎病史的不育男性的精子图谱数据进行了统计计算,并与200名未患该病的不育男性的数据以及22名健康有生育能力男性的数据进行了关联分析。作者指出,与无流行性腮腺炎病史的不育男性相比,有腮腺炎病史的不育男性射精精子含量显著降低(p<0.05),形态正常的精子数量也显著减少(p<0.001)。

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