社区老年人身高与认知功能的关系：翰林老龄化研究。
The Relationship between Height and Cognitive Function among Community-dwelling Elderly: Hallym Aging Study.
机构信息
Department of Social and Preventive Medicine, Hallym University College of Medicine, Chuncheon, Korea. ; Hallym Research Institute of Clinical Epidemiology, Chuncheon, Korea.
出版信息
Epidemiol Health. 2013 Apr 30;35:e2013002. doi: 10.4178/epih/e2013002. Print 2013.
OBJECTIVES
Height is known as an index that reflects the environment of the fetal, childhood, and adolescent periods, which affect adult health. This study was conducted to elucidate whether height is associated with cognitive impairment in community-dwelling elders in Korea.
METHODS
The study subjects were recruited among community dwelling elderly individuals aged 65 or over who participated in the 2004 Hallym Aging Study. They were invited to a general hospital and were evaluated for socioeconomic status, smoking history, and various clinical measures. Cognitive function measurement was performed using the Korean-Mini Mental State Examination. Logistic regression was used to evaluate the association between height and cognitive function.
RESULTS
After adjusting for potential covariates such as age and education, the smallest group was associated with higher risk of cognitive impairment compared with the tallest group among elderly men (odds ratio [OR], 4.20; 95% confidence interval [CI], 1.02-17.36), but not among elderly women (OR,1.65; 95% CI, 0.62-4.40).
CONCLUSIONS
The reason for this difference according to sex may be explained by the differential effects of education on cognitive function by sex. A larger population-based prospective cohort study is needed to examine the association between height and cognitive function according to sex.
目的
身高是反映胎儿、儿童和青少年时期环境的指标，这些环境会影响成人健康。本研究旨在阐明身高是否与韩国社区老年人的认知障碍有关。
方法
本研究的研究对象是参加 2004 年翰林衰老研究的年龄在 65 岁及以上的社区居住老年人。他们被邀请到一家综合医院，评估其社会经济地位、吸烟史和各种临床指标。认知功能测量采用韩国迷你精神状态检查。使用逻辑回归评估身高与认知功能之间的关系。
结果
在调整了年龄和教育等潜在混杂因素后，与最高身高组相比，老年男性中最矮小的身高组认知障碍的风险更高（比值比 [OR]，4.20；95%置信区间 [CI]，1.02-17.36），但在老年女性中并非如此（OR，1.65；95% CI，0.62-4.40）。
结论
根据性别出现这种差异的原因可能是教育对认知功能的性别差异影响不同。需要进行更大的基于人群的前瞻性队列研究，以根据性别检查身高与认知功能之间的关系。
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