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中国农村低收入老年人中身高与认知障碍的性别相关关联:一项基于人群的横断面研究。

Sex-related associations between body height and cognitive impairment among low-income elderly adults in rural China: a population-based cross-sectional study.

机构信息

Department of Neurology, Yiwu Central Hospital & The Affiliated Yiwu Hospital of Wenzhou Medical College, 699 Jiangdong Road, Yiwu City, 322000, Zhejiang, China.

Department of Emergency Medicine, Yiwu Central Hospital &The Affiliated Yiwu Hospital of Wenzhou Medical College, 699 Jiangdong Road, Yiwu City, 322000, Zhejiang, China.

出版信息

Biol Sex Differ. 2021 Dec 6;12(1):65. doi: 10.1186/s13293-021-00408-w.

Abstract

BACKGROUND

Body height is a marker of childhood health and cumulative net nutrition during growth periods. However, sex-specific associations between body height and cognitive impairment are not well known in northern rural China.

METHODS

We assessed sex differences in the association between body height and cognitive impairment in a low-income elderly population in rural China. A population-based cross-sectional study was conducted from April 2014 to August 2014 to collect basic information from elderly residents aged 60 years and older in rural areas of Tianjin, China. Body height and Mini Mental State Examination (MMSE) scores were measured, and the relationships between these variables were assessed.

RESULTS

A total of 1081 residents with a mean age of 67.7 years were enrolled in this study. After adjusting for age, educational attainment, smoking status, drinking status, and the presence of hypertension, diabetes, and hypercholesterolemia, higher body height was found to be associated with a decreased prevalence of cognitive impairment in elderly men. Each 1-dm increase in height was associated with a 37% decrease in the prevalence of cognitive impairment. However, there was no significant association between body height and cognitive impairment among elderly women.

CONCLUSION

In conclusion, shorter body height was related to cognitive impairment independently of age, educational attainment, lifestyle factors, and health-related comorbid factors among low-income elderly men in rural China. Accordingly, shorter elderly men may be targeted for effective dementia prevention in rural China.

摘要

背景

身高是儿童健康和生长期间累积净营养的标志。然而,在中国北方农村,身高与认知障碍之间的性别特异性关联尚不清楚。

方法

我们评估了中国农村低收入老年人群体中身高与认知障碍之间的关联存在性别差异。本研究采用基于人群的横断面研究,于 2014 年 4 月至 8 月期间收集中国天津市农村地区 60 岁及以上老年居民的基本信息。测量身高和简易精神状态检查(MMSE)评分,并评估这些变量之间的关系。

结果

本研究共纳入 1081 名平均年龄为 67.7 岁的居民。在校正年龄、受教育程度、吸烟状况、饮酒状况以及高血压、糖尿病和高胆固醇血症的存在后,发现较高的身高与老年男性认知障碍的患病率降低有关。身高每增加 1 厘米,认知障碍的患病率降低 37%。然而,身高与老年女性的认知障碍之间没有显著关联。

结论

总之,在中国农村低收入老年男性中,身高与认知障碍独立相关,与年龄、受教育程度、生活方式因素以及与健康相关的合并症因素无关。因此,在中国农村,较矮的老年男性可能是有效的痴呆预防目标人群。

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Brain structure mediates the association between height and cognitive ability.大脑结构介导身高与认知能力之间的关联。
Brain Struct Funct. 2018 Sep;223(7):3487-3494. doi: 10.1007/s00429-018-1675-4. Epub 2018 May 11.

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