Temming Lorene, Franco Albert, Istwan Niki, Rhea Debbie, Desch Cheryl, Stanziano Gary, Joy Saju
Department of Obstetrics and Gynecology, Carolinas Medical Center , Charlotte, NC , USA .
J Matern Fetal Neonatal Med. 2014 Jan;27(1):84-8. doi: 10.3109/14767058.2013.806473. Epub 2013 Jun 21.
To examine the influence of nausea and vomiting of pregnancy (NVP) on pregnancy outcomes.
Outcomes were compared for primigravidas with a current singleton gestation enrolled at <20 weeks' gestation in a maternity risk screening and education program (n = 81 486). Patient-reported maternal characteristics and pregnancy outcomes were compared for women with and without NVP and within the NVP group for those with and without poor weight gain.
6.4% of women reported NVP as a pregnancy complication. Women reporting NVP were more likely to be younger, obese, single and smoke. They had higher rates of preterm delivery, pregnancy-induced hypertension and low birth weight <2500 g. Almost one-quarter of women with NVP had lower than recommended weight gain. Poor weight gain was associated with a higher incidence of adverse outcomes. Obesity, tobacco use and poor pregnancy weight gain independently increased the odds of an adverse outcome.
NVP and subsequent poor weight gain may be associated with adverse pregnancy outcomes.
探讨妊娠恶心和呕吐（NVP）对妊娠结局的影响。
在一项孕产妇风险筛查和教育项目中，对妊娠<20周的初产妇单胎妊娠结局进行比较（n = 81486）。比较有和没有NVP的女性以及NVP组中有和没有体重增加不佳的女性的患者报告的孕产妇特征和妊娠结局。
6.4%的女性报告NVP为妊娠并发症。报告有NVP的女性更可能年龄较小、肥胖、单身且吸烟。她们的早产、妊娠高血压和出生体重<2500g的发生率更高。几乎四分之一有NVP的女性体重增加低于推荐值。体重增加不佳与不良结局的发生率较高相关。肥胖、吸烟和妊娠体重增加不佳独立增加了不良结局的几率。
NVP及随后体重增加不佳可能与不良妊娠结局有关。
