Ayorinde Abimbola Adebukola, Porteous Terry, Sharma Pawana
Epidemiology Group, University of Aberdeen, Aberdeen, UK.
Int J Pharm Pract. 2013 Dec;21(6):349-61. doi: 10.1111/ijpp.12041. Epub 2013 May 20.
The aim of this systematic review was to assess the published evidence about the feasibility and acceptability of community pharmacy-based screening for major diseases.
Studies published between January 1990 and August 2012 involving community pharmacy-based screening interventions, published in the English language, were identified from electronic databases. Reference lists of included studies were also searched.
Fifty studies (one randomised controlled trial, two cluster randomised studies, five non-randomised comparative studies and 42 uncontrolled studies) were included. The quality of most of these was assessed as poor. Screening was mostly opportunistic and screening tools included questionnaires or risk assessment forms, medical equipment to make physiological measurements, or a combination of both. Few studies assessed the accuracy of pharmacy-based screening tools. More than half of the screening interventions included an element of patient education. The proportion of screened individuals, identified with disease risk factors or the disease itself, ranged from 4% to 89%. Only 10 studies reported any economic information. Where assessed, patient satisfaction with pharmacy-based screening was high, but individuals who screened positive often did not follow pharmacist advice to seek further medical help.
Available evidence suggests that screening for some diseases in community pharmacies is feasible. More studies are needed to compare effectiveness and cost-effectiveness of pharmacy-based screening with screening by other providers. Strategies to improve screening participants' adherence to pharmacist advice also need to be explored. This systematic review will help to inform future studies wishing to develop community pharmacy-based screening interventions.
本系统评价旨在评估已发表的关于社区药房开展重大疾病筛查的可行性和可接受性的证据。
从电子数据库中检索1990年1月至2012年8月间发表的、涉及基于社区药房的筛查干预措施且为英文的研究。还对纳入研究的参考文献列表进行了检索。
共纳入50项研究(1项随机对照试验、2项整群随机研究、5项非随机对照研究和42项非对照研究)。其中大多数研究的质量被评估为较差。筛查大多是机会性的,筛查工具包括问卷或风险评估表、用于进行生理测量的医疗设备或两者结合。很少有研究评估基于药房的筛查工具的准确性。超过一半的筛查干预措施包含患者教育内容。被筛查出有疾病风险因素或疾病本身的个体比例在4%至89%之间。只有10项研究报告了任何经济信息。在进行评估的地方,患者对基于药房的筛查满意度较高,但筛查呈阳性的个体往往不遵循药剂师的建议寻求进一步医疗帮助。
现有证据表明在社区药房对某些疾病进行筛查是可行的。需要更多研究来比较基于药房的筛查与其他提供者进行的筛查的有效性和成本效益。还需要探索提高筛查参与者遵循药剂师建议的策略。本系统评价将有助于为未来希望开展基于社区药房的筛查干预措施的研究提供信息。