Unich P P
Vrach Delo. 1990 Mar(3):102-4.
Muscle oxygen tension and local tissue blood flow were studied in 33 patients with multiple sclerosis in the course of complex treatment. The first stages of the disease were characterized by an increase of muscle oxygen tension while time of its delivery was delayed due to increased rate of local tissue blood flow and increased capillary permeability. Severe forms of multiple sclerosis are characterized by a reduced pO2 and local tissue blood flow. It is concluded that indices of tissue oxygen balance and microcirculation may serve as criteria of the severity of the disease and efficacy of instituted treatment.
在33例接受综合治疗的多发性硬化症患者中，对肌肉氧张力和局部组织血流进行了研究。疾病的早期阶段表现为肌肉氧张力增加，而由于局部组织血流速率增加和毛细血管通透性增加，氧输送时间延迟。严重形式的多发性硬化症表现为氧分压和局部组织血流降低。得出的结论是，组织氧平衡和微循环指标可作为疾病严重程度和所采用治疗效果的标准。
