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分叉病变 T 支架术及小嵴技术的长期临床结果。

The long-term clinical outcome of T-stenting and small protrusion technique for coronary bifurcation lesions.

机构信息

Interventional Cardiology Unit, San Raffaele Scientific Institute, Milan, Italy.

出版信息

JACC Cardiovasc Interv. 2013 Jun;6(6):554-61. doi: 10.1016/j.jcin.2013.01.137. Epub 2013 May 15.

Abstract

OBJECTIVES

This study sought to report long-term clinical outcomes in patients treated with the provisional T-stenting and small protrusion (TAP) technique.

BACKGROUND

Several strategies have been proposed for treating bifurcation lesions, each with its own merits and technical challenges. The TAP technique is a relatively new strategy that is technically less challenging, ensures complete coverage of the side-branch ostium, and minimizes stent overlap. Although there is reasonable amount of data for other bifurcation strategies, the long-term clinical outcomes for TAP technique are limited.

METHODS

We retrospectively evaluated all patients who underwent TAP technique with drug-eluting stents between July 2005 and January 2012. The measured endpoints at follow-up were major adverse cardiac events defined as composite of cardiac death, myocardial infarction, and target vessel revascularization.

RESULTS

A total of 95 patients (81.1% men) with a mean age of 64.8 years underwent TAP stenting. Procedural success was achieved in 100% of cases. True bifurcation was observed in 75 (78.9%) patients. First-generation drug-eluting stents were used in 55.8% of patients. The outcome rates at 3-year follow-up of major adverse cardiac events, cardiac death/follow-up myocardial infarction, target vessel revascularization, and target lesion revascularization were 12.9%, 3.1%, 9.7%, and 5.1%, respectively. There were no cases of follow-up myocardial infarction or stent thrombosis (definite and probable).

CONCLUSIONS

These results demonstrate that TAP technique is associated with acceptable clinical outcomes with no episodes of definite and probable stent thrombosis. Further studies should compare TAP technique with other 2-stent strategies.

摘要

目的

本研究旨在报告采用临时 T 型支架和小突出(TAP)技术治疗的患者的长期临床结果。

背景

已经提出了几种治疗分叉病变的策略,每种策略都有其自身的优点和技术挑战。TAP 技术是一种相对较新的策略,技术难度较小,可确保完全覆盖侧支开口,并最小化支架重叠。尽管其他分叉策略有相当多的数据,但 TAP 技术的长期临床结果有限。

方法

我们回顾性评估了 2005 年 7 月至 2012 年 1 月期间接受药物洗脱支架 TAP 技术治疗的所有患者。随访时的测量终点是主要不良心脏事件,定义为心脏死亡、心肌梗死和靶血管血运重建的复合事件。

结果

共有 95 例(81.1%为男性)患者,平均年龄为 64.8 岁,接受了 TAP 支架置入术。100%的病例达到了手术成功。75 例(78.9%)患者为真性分叉病变。第一代药物洗脱支架在 55.8%的患者中使用。3 年随访时,主要不良心脏事件、心脏死亡/随访心肌梗死、靶血管血运重建和靶病变血运重建的发生率分别为 12.9%、3.1%、9.7%和 5.1%。无随访心肌梗死或支架血栓形成(确定和可能)病例。

结论

这些结果表明,TAP 技术与可接受的临床结果相关,且无确定和可能的支架血栓形成事件。应进一步研究比较 TAP 技术与其他双支架策略。

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