Dézsi Csaba A, Andréka Judit, Sayour Amer M, Deák Mónika, Szentes Veronika, Sebők Zoltán, Fi Zsolt, Achim Alexandru, Ruzsa Zoltán
Faculty of Health and Sports Sciences, Department of Health, and Nursing Sciences, Széchenyi István University, Győr, Hungary.
Department of Cardiology, Győr-Moson-Sopron County Petz A. University Teaching Hospital, Győr, Hungary.
Future Cardiol. 2024 Dec-Dec;20(15-16):837-842. doi: 10.1080/14796678.2024.2435205. Epub 2024 Dec 4.
Data about coronary bifurcations treated with ultrathin strut drug-eluting stents (DES) using T-and-protrusion (TAP) technique is limited.
In this study, a total of 84 consecutive patients, who underwent bifurcation percutaneous coronary intervention (PCI) with TAP technique using Orsiro® DES (Biotronik, Berlin, Germany), were included. All pre- and post-procedural data, as well as 1- and 2-year follow-up angiograms, were analyzed. Primary endpoints were procedural success and target lesion failure (TLF); secondary endpoints were all-cause mortality and major adverse cardiac and cerebrovascular events (MACCE) during follow-up.
Procedural success was achieved in 100% of cases. TLF rate was higher in patients presented with acute coronary syndrome compared to the ones with chronic coronary syndrome (19% vs. 5% = 0.09). All-cause mortality was 30% during follow-up, from which 26% was due to non-cardiovascular cause, and the MACCE rate was 46%.
Coronary bifurcations treated with ultrathin strut DES showed good short-term results and were associated with acceptable cardiovascular mortality. However, in these long-term patients, the rate of MACCE and non-cardiovascular death were rather high.
关于使用T型和突出型（TAP）技术的超薄支架药物洗脱支架（DES）治疗冠状动脉分叉病变的数据有限。
在本研究中，纳入了总共84例连续患者，他们使用Orsiro® DES（德国柏林百多力公司）通过TAP技术接受了分叉经皮冠状动脉介入治疗（PCI）。分析了所有术前和术后数据以及1年和2年的随访血管造影图像。主要终点是手术成功率和靶病变失败（TLF）；次要终点是随访期间的全因死亡率和主要不良心脑血管事件（MACCE）。
100%的病例实现了手术成功。与慢性冠状动脉综合征患者相比，急性冠状动脉综合征患者的TLF率更高（19%对5% = 0.09）。随访期间全因死亡率为30%，其中26%是由于非心血管原因，MACCE率为46%。
使用超薄支架DES治疗的冠状动脉分叉病变显示出良好的短期结果，并且与可接受的心血管死亡率相关。然而，在这些长期患者中，MACCE和非心血管死亡的发生率相当高。
