酚可溶性调节素，葡萄球菌毒力因子大混乱中的地狱犬。
Phenol-soluble modulins, hellhounds from the staphylococcal virulence-factor pandemonium.
机构信息
Department of Medical Microbiology, University of Groningen and University Medical Center Groningen, Hanzeplein 1, P.O. box 30001, 9700 RB Groningen, the Netherlands.
出版信息
Trends Microbiol. 2013 Jul;21(7):313-5. doi: 10.1016/j.tim.2013.04.007. Epub 2013 May 14.
Phenol-soluble modulins are secreted peptides with multiple functions in Staphylococcus aureus pathogenesis and spreading. Recent studies by Otto and coworkers show that these hellhounds of the staphylococcal virulence-factor pandemonium are unleashed through an essential ABC transporter, which represents an exciting new target for stopping the spread of this important pathogen.
酚可溶性调节素是具有多种功能的分泌肽，在金黄色葡萄球菌发病机制和传播中起作用。最近 Otto 及其同事的研究表明，这些来自金黄色葡萄球菌毒力因子混乱的地狱犬是通过一种必需的 ABC 转运蛋白释放的，这为阻止这种重要病原体的传播提供了一个令人兴奋的新靶点。
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