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常规冠状动脉计算机断层血管造影术与减少急诊科胸痛分诊时不必要的住院人数、住院时间、再入院率和经皮冠状动脉介入治疗的相关性。

Associations between routine coronary computed tomographic angiography and reduced unnecessary hospital admissions, length of stay, recidivism rates, and invasive coronary angiography in the emergency department triage of chest pain.

机构信息

Department of Radiology, Stony Brook Medicine, State University of New York-Stony Brook University, Stony Brook, NY 11794, USA.

出版信息

J Am Coll Cardiol. 2013 Aug 6;62(6):543-52. doi: 10.1016/j.jacc.2013.04.040. Epub 2013 May 15.

Abstract

OBJECTIVES

This study was designed to assess the effects on resource utilization of routine coronary computed tomographic angiography (CCTA) in triaging chest pain patients in the emergency department (ED).

BACKGROUND

The routine use of CCTA for ED evaluation of chest pain is feasible and safe.

METHODS

We conducted a retrospective multivariate analysis of data from two risk-matched cohorts of 894 ED patients presenting with chest pain to assess the impact of CCTA versus standard evaluation on admissions rate, length of stay, major adverse cardiovascular event rates, recidivism rates, and downstream resource utilization.

RESULTS

The overall admission rate was lower with CCTA (14% vs. 40%; p < 0.001). Standard evaluation was associated with a 5.5-fold greater risk for admission (odds ratio [OR]: 5.53; p < 0.001). Expected ED length of stay with standard evaluation was about 1.6 times longer (OR: 1.55; p < 0.001). There were no differences in the rates of death and acute myocardial infarction within 30 days of the index visit between the two groups. The likelihood of returning to the ED within 30 days for recurrent chest pain was 5 times greater with standard evaluation (OR: 5.06; p = 0.022). Standard evaluation was associated with a 7-fold greater likelihood of invasive coronary angiography without revascularization (OR: 7.17; p < 0.001), while neither group was significantly more likely to receive revascularization (OR: 2.06; p = 0.193). The median radiation dose with CCTA was 5.88 mSv (n = 1039; confidence interval: 5.2 to 6.4).

CONCLUSIONS

The routine use of CCTA in ED evaluation of chest pain reduces healthcare resource utilization.

摘要

目的

本研究旨在评估常规冠状动脉计算机断层扫描血管造影(CCTA)在急诊科(ED)分诊胸痛患者中的资源利用效果。

背景

ED 评估胸痛时常规使用 CCTA 是可行且安全的。

方法

我们对来自两个风险匹配的 ED 胸痛患者队列(共 894 例患者)的回顾性多变量数据分析,以评估 CCTA 与标准评估对入院率、住院时间、主要不良心血管事件发生率、复发率和下游资源利用的影响。

结果

CCTA 组的总体入院率较低(14% vs. 40%;p < 0.001)。标准评估与入院风险增加 5.5 倍相关(优势比[OR]:5.53;p < 0.001)。标准评估预计 ED 住院时间延长约 1.6 倍(OR:1.55;p < 0.001)。两组在指数就诊后 30 天内的死亡率和急性心肌梗死发生率无差异。标准评估组 30 天内因复发性胸痛返回 ED 的可能性增加 5 倍(OR:5.06;p = 0.022)。标准评估与无血运重建的侵入性冠状动脉造影的可能性增加 7 倍相关(OR:7.17;p < 0.001),而两组接受血运重建的可能性均无显著差异(OR:2.06;p = 0.193)。CCTA 的中位辐射剂量为 5.88 mSv(n = 1039;置信区间:5.2 至 6.4)。

结论

ED 评估胸痛时常规使用 CCTA 可减少医疗保健资源的利用。

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