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勒米尔综合征:被遗忘的疾病。

Lemierre's syndrome: the forgotten disease.

作者信息

Johannesen Katrine, Bødtger Uffe, Heltberg Ole

机构信息

Department of Lung Medicine, Næstved Hospital, Ringstedgade 61, 4700, Næstved, Denmark,

出版信息

J Thromb Thrombolysis. 2014 Apr;37(3):246-8. doi: 10.1007/s11239-013-0931-y.

DOI:10.1007/s11239-013-0931-y
PMID:23686643
Abstract

Lemierre's syndrome is an often un-diagnosed disease seen in previously healthy young subjects, presenting with symptoms of pharyngitis, fever and elevated markers of inflammation. The syndrome is characterised by infectious thrombosis of the jugular vein due to infection with Fusobacteria, causing a variety of infectious complications. Rapid diagnosis and treatment is necessary to avoid severe complications or death. Close collaboration with local microbiologist is pivotal. Treatment consists of longterm treatment with penicillin and metronidazole. This is a case report of Lemierre's syndrome.

摘要

勒米尔综合征是一种常见于既往健康的年轻人群中、常未被诊断的疾病,表现为咽炎、发热及炎症指标升高。该综合征的特征是由梭杆菌感染导致颈静脉感染性血栓形成,进而引发各种感染性并发症。为避免严重并发症或死亡,快速诊断和治疗十分必要。与当地微生物学家密切合作至关重要。治疗包括长期使用青霉素和甲硝唑。这是一例勒米尔综合征的病例报告。

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Lemierre's syndrome: the forgotten disease.勒米尔综合征:被遗忘的疾病。
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本文引用的文献

1
Lemierre's syndrome due to Fusobacterium necrophorum.坏死梭杆菌引起的李-孟二氏综合征。
Lancet Infect Dis. 2012 Oct;12(10):808-15. doi: 10.1016/S1473-3099(12)70089-0. Epub 2012 May 25.
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Lemierre syndrome: a case report.勒米尔氏综合征:一例报告。
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Lemierre's syndrome: A systematic review.勒米尔综合征:一项系统评价。
韩国一家三级保健医院感染患者的临床差异和分离株的抗菌药物敏感性。
Ann Lab Med. 2022 Mar 1;42(2):188-195. doi: 10.3343/alm.2022.42.2.188.
4
Differences in mortality in Fusobacterium necrophorum and Fusobacterium nucleatum infections detected by culture and 16S rRNA gene sequencing.通过培养和 16S rRNA 基因测序检测到坏死梭杆菌和核梭杆菌感染的死亡率差异。
Eur J Clin Microbiol Infect Dis. 2019 Jan;38(1):75-80. doi: 10.1007/s10096-018-3394-4. Epub 2018 Oct 29.
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Lemierre's syndrome: current perspectives on diagnosis and management.勒米尔综合征:诊断与管理的当前观点
Infect Drug Resist. 2016 Sep 14;9:221-227. doi: 10.2147/IDR.S95050. eCollection 2016.
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Bad news itself or just the messenger? The high mortality of Fusobacterium spp. infections is related to disseminated malignancy and other comorbidities.是坏消息本身还是仅仅是传递消息的人?具核梭杆菌感染的高死亡率与播散性恶性肿瘤和其他合并症有关。
Eur Clin Respir J. 2016 May 10;3:30287. doi: 10.3402/ecrj.v3.30287. eCollection 2016.
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Imaging of connective tissue diseases of the head and neck.头颈部结缔组织疾病的影像学检查
Neuroradiol J. 2016 Jun;29(3):222-30. doi: 10.1177/1971400916639605. Epub 2016 Mar 17.
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Lemierre's Syndrome.勒米尔综合征
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Human necrobacillosis, with emphasis on Lemierre's syndrome.人类坏死杆菌病,重点介绍勒米耶综合征。
Clin Infect Dis. 2000 Aug;31(2):524-32. doi: 10.1086/313970. Epub 2000 Sep 14.