Department of Neurology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
Stroke. 2013 Jul;44(7):2013-5. doi: 10.1161/STROKEAHA.113.001111. Epub 2013 May 16.
We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke.
We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI.
NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55-4.07). An increase in burden count of NRCA was also associated with poor outcomes.
The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.
我们研究了非相关脑动脉粥样硬化（NRCA）在急性脑卒中患者中的存在是否具有预后价值。
我们比较了 780 例首次急性脑梗死患者的预后，这些患者均接受了脑血管造影和弥散加权 MRI 检查。
267 例（34.2%）患者存在 NRCA。多变量分析表明，NRCA 的存在与第 1 天内 NIHSS 评分的改善程度较低（P=0.004）以及 3 个月后（改良 Rankin 量表评分>2）的不良功能结局独立相关（比值比，2.51；95%置信区间，1.55-4.07）。NRCA 的负担计数增加也与不良结局相关。
急性脑梗死患者 NRCA 的存在和负担计数与不良神经结局相关。
