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生物可吸收雷帕霉素洗脱血管支架(BVS)在 ST 段抬高型心肌梗死(STEMI)患者中的植入。

Everolimus-eluting bioresorbable vascular scaffold (BVS) implantation in patients with ST-segment elevation myocardial infarction (STEMI).

机构信息

Cardiac Department, National University Heart Centre Singapore, Singapore.

出版信息

EuroIntervention. 2013 Aug 22;9(4):501-4. doi: 10.4244/EIJV9I4A80.

Abstract

AIMS

Recent studies have demonstrated favourable clinical outcomes for the everolimus-eluting bioresorbable vascular scaffold (BVS) ABSORB™ in patients with stable coronary artery disease. There are currently no data on its use in patients with ST-segment elevation myocardial infarction (STEMI). We assessed the safety and impact of BVS in the setting of primary percutaneous coronary intervention (PCI) in patients presenting with STEMI to our institution.

METHODS AND RESULTS

A total of 11 patients who underwent primary PCI with intent for BVS implantation between October 2012 and April 2013 at our institution were included. Median follow-up period was 53.0 ± 45.9 days. One patient presented to the hospital with cardiogenic shock and subsequently died. The other 10 patients did not have any major adverse cardiac events (MACE). There were no acute or subacute stent thromboses at short-term follow-up.

CONCLUSIONS

These are the first real-world data using BVS in patients with STEMI. The ABSORB™ BVS may be safely used in patients with STEMI undergoing primary PCI with favourable short-term outcome.

摘要

目的

最近的研究表明,在稳定性冠心病患者中,依维莫司洗脱的生物可吸收血管支架(BVS)ABSORB™具有良好的临床疗效。目前尚无关于其在 ST 段抬高型心肌梗死(STEMI)患者中应用的数据。我们评估了在我院接受直接经皮冠状动脉介入治疗(PCI)的 STEMI 患者中,BVS 的安全性和影响。

方法和结果

共纳入 2012 年 10 月至 2013 年 4 月期间在我院接受直接 PCI 并计划植入 BVS 的 11 例患者。中位随访时间为 53.0±45.9 天。1 例患者因心源性休克就诊,随后死亡。其他 10 例患者均未发生主要不良心脏事件(MACE)。短期随访期间无急性或亚急性支架血栓形成。

结论

这是在 STEMI 患者中使用 BVS 的首批真实世界数据。ABSORB™ BVS 可安全用于接受直接 PCI 的 STEMI 患者,短期预后良好。

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