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Gene therapy to prolong reproductive life.

作者信息

Wolfe Andrew, Divall Sara

机构信息

Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

出版信息

Endocrinology. 2013 Jun;154(6):1965-6. doi: 10.1210/en.2013-1384.

DOI:10.1210/en.2013-1384
PMID:23687112
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5393328/
Abstract
摘要

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本文引用的文献

1
Hypothalamic IGF-I gene therapy prolongs estrous cyclicity and protects ovarian structure in middle-aged female rats.下丘脑 IGF-I 基因治疗可延长中年雌性大鼠动情周期并保护卵巢结构。
Endocrinology. 2013 Jun;154(6):2166-73. doi: 10.1210/en.2013-1069. Epub 2013 Apr 12.
2
Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders.大脑的分子衰老、神经可塑性以及对抑郁症和其他脑部相关疾病的易感性。
Dialogues Clin Neurosci. 2013 Mar;15(1):53-65. doi: 10.31887/DCNS.2013.15.1/esibille.
3
Differential effects of hypothalamic IGF-I on gonadotropin releasing hormone neuronal activation during steroid-induced LH surges in young and middle-aged female rats.类固醇诱导的年轻和中年雌性大鼠 LH 峰期间，下丘脑 IGF-I 对 GnRH 神经元激活的差异影响。
Endocrinology. 2011 Nov;152(11):4276-87. doi: 10.1210/en.2011-1051. Epub 2011 Sep 13.
4
Restorative effect of intracerebroventricular insulin-like growth factor-I gene therapy on motor performance in aging rats.脑室内注射胰岛素样生长因子 - I 基因治疗对老年大鼠运动功能的恢复作用。
Neuroscience. 2011 Mar 17;177:195-206. doi: 10.1016/j.neuroscience.2011.01.013. Epub 2011 Jan 14.
5
Divergent roles of growth factors in the GnRH regulation of puberty in mice.生长因子在 GnRH 调控小鼠青春期中的不同作用。
J Clin Invest. 2010 Aug;120(8):2900-9. doi: 10.1172/JCI41069. Epub 2010 Jul 12.
6
Hypothalamic insulin-like growth factor-I receptors are necessary for hormone-dependent luteinizing hormone surges: implications for female reproductive aging.下丘脑胰岛素样生长因子-I 受体对于激素依赖性促黄体生成素激增是必要的：对女性生殖衰老的影响。
Endocrinology. 2010 Mar;151(3):1356-66. doi: 10.1210/en.2009-1009. Epub 2010 Jan 22.
7
Menopause and hypothalamic-pituitary sensitivity to estrogen.更年期与下丘脑 - 垂体对雌激素的敏感性
JAMA. 2004 Dec 22;292(24):2991-6. doi: 10.1001/jama.292.24.2991.
8
[RESULTS PROVIDED BY HETEROCHRONIC GRAFTS OF THE OVARIES IN THE STUDY OF THE HYPOTHALAMO-HYPOPHYSO-OVARIAN REGULATION OF SENILE RATS].[老年大鼠下丘脑-垂体-卵巢调节研究中卵巢异时移植提供的结果]
Gerontologia. 1964;10:65-75.
9
A test of evolutionary theories of aging.衰老进化理论的一项测试。
Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14286-91. doi: 10.1073/pnas.222326199. Epub 2002 Oct 17.
10
Alterations in hypothalamic insulin-like growth factor-I and its associations with gonadotropin releasing hormone neurones during reproductive development and ageing.下丘脑胰岛素样生长因子-I的变化及其在生殖发育和衰老过程中与促性腺激素释放激素神经元的关联。
J Neuroendocrinol. 2001 Aug;13(8):728-36. doi: 10.1046/j.1365-2826.2001.00686.x.