结直肠癌：结直肠癌分类的新时代终于来临了吗？ - Suppr

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Colorectal cancer: Is the new era of colorectal cancer classification finally here?

作者信息

Nagtegaal Iris D, van Krieken J Han J M

出版信息

Nat Rev Gastroenterol Hepatol. 2013 Jul;10(7):391-3. doi: 10.1038/nrgastro.2013.90. Epub 2013 May 21.

DOI:10.1038/nrgastro.2013.90

PMID:23689082

Abstract

摘要

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本文引用的文献

Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions.预后不良的结肠癌由分子上明显不同的亚型定义，并由锯齿状前体病变发展而来。

Nat Med. 2013 May;19(5):614-8. doi: 10.1038/nm.3174. Epub 2013 Apr 14.

A colorectal cancer classification system that associates cellular phenotype and responses to therapy.一种与细胞表型和治疗反应相关的结直肠癌分类系统。

Nat Med. 2013 May;19(5):619-25. doi: 10.1038/nm.3175. Epub 2013 Apr 14.

Molecular patterns in the evolution of serrated lesion of the colorectum.结直肠锯齿状病变演进中的分子模式。

Int J Cancer. 2013 Apr 15;132(8):1800-10. doi: 10.1002/ijc.27869. Epub 2012 Oct 17.

ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer.ZEB/miR-200 反馈环：癌症信号转导的十字路口。

Int J Cancer. 2013 Feb 15;132(4):745-54. doi: 10.1002/ijc.27708. Epub 2012 Jul 21.

Biomarkers as disease definition: mantle cell lymphoma as an example.标志物作为疾病定义：以套细胞淋巴瘤为例。

Proteomics Clin Appl. 2010 Dec;4(12):922-5. doi: 10.1002/prca.201000048.

Microsatellite instability as a marker of prognosis and response to therapy: a meta-analysis of colorectal cancer survival data.微卫星不稳定性作为预后和治疗反应的标志物：对结直肠癌生存数据的荟萃分析。

Eur J Cancer. 2010 Oct;46(15):2788-98. doi: 10.1016/j.ejca.2010.05.009. Epub 2010 Jun 4.

Loss of membranous Ep-CAM in budding colorectal carcinoma cells.萌芽状态的结肠癌细胞中膜性上皮细胞粘附分子（Ep-CAM）的缺失。

Mod Pathol. 2007 Feb;20(2):221-32. doi: 10.1038/modpathol.3800733.

American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer.美国临床肿瘤学会关于II期结肠癌辅助化疗的建议。

J Clin Oncol. 2004 Aug 15;22(16):3408-19. doi: 10.1200/JCO.2004.05.063. Epub 2004 Jun 15.

CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: an immunohistochemical survey of 476 primary and metastatic carcinomas.CDX2，一种高度敏感且特异的肠道原发性腺癌标志物：476例原发性和转移性癌的免疫组化研究

Am J Surg Pathol. 2003 Mar;27(3):303-10. doi: 10.1097/00000478-200303000-00003.

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