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[结直肠癌的分类:格拉茨病理研究所辖区的当前结果]

[Classification of colorectal cancers: current results from the catchment area of the Graz Institute of Pathology].

作者信息

Klimpfinger M, Hauser H, Beham A, Denk H

机构信息

Institut für Pathologische Anatomie, Universität Graz.

出版信息

Wien Med Wochenschr. 1988 Jun 30;138(11-12):267-70.

PMID:3176506
Abstract

In comparison with the results of Dukes the percentage of stage Dukes A of colorectal carcinomas could be increased from 15% to about 27%, whereas the percentage of stage Dukes C decreased from 51 to 40% in some international medical centers during the seventies of this century. Our results in Styria are comparable. However, there was no further progress in the early diagnosis of colorectal carcinomas in Styria from 1984 to 1986 (42% of Dukes C stage cases) as compared with 1974 to 1979 (41% of Dukes C stage cases). The percentage of endoscopically removed tumors increased from 3% (1974 bis 1979) to 9% (1984 to 1986) of all curatively treated carcinomas. Because of the fact that the endoscopically removed tumors (stage pT1pNx) could not be classified according to Dukes, the percentage of Dukes stage A decreased from 30% (1974 to 1979) to 24% (1984 to 1986). But the small numbers of endoscopically removed tumors did not significantly influence the percentage of Dukes C stages. There was only partial success in the predominantly rural areas in which the percentage of Dukes C stages decreased from 47% (1974 to 1979) to 39% (1984 to 1986). 39% Dukes stage C in rural areas correspond to the percentage of the predominantly municipal areas (40%). This progress can be explained by the availability of colonoscopy to all hospitals in 1984 to 1986, which was not the case previously.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

与杜克斯分期(Dukes staging)的结果相比,本世纪七十年代,在一些国际医疗中心,结直肠癌的杜克斯A期比例从15%提高到了约27%,而杜克斯C期比例则从51%降至40%。我们在施蒂里亚州(Styria)的结果与之相当。然而,1984年至1986年期间,施蒂里亚州结直肠癌的早期诊断情况与1974年至1979年相比并无进一步进展(杜克斯C期病例占42%)。在所有接受根治性治疗的癌症中,通过内镜切除的肿瘤比例从1974年至1979年的3%增至1984年至1986年的9%。由于内镜切除的肿瘤(pT1pNx期)无法按照杜克斯分期进行分类,杜克斯A期的比例从1974年至1979年的30%降至1984年至1986年的24%。但内镜切除的肿瘤数量较少,对杜克斯C期的比例没有显著影响。在以农村为主的地区,仅取得了部分成功,杜克斯C期的比例从1974年至1979年的47%降至1984年至1986年的39%。农村地区39%的杜克斯C期与以城市为主的地区比例(40%)相当。这一进展可以解释为,1984年至1986年期间所有医院都可进行结肠镜检查,而此前并非如此。(摘要截选至250词)

相似文献

1
[Classification of colorectal cancers: current results from the catchment area of the Graz Institute of Pathology].[结直肠癌的分类:格拉茨病理研究所辖区的当前结果]
Wien Med Wochenschr. 1988 Jun 30;138(11-12):267-70.
2
[The classification system of Dukes and its modification for rectal and colonic cancers].
Helv Chir Acta. 1981 Apr;48(1-2):265-72.
3
Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer.端粒酶与端粒长度在癌前病变发展为结直肠癌过程中的作用
Clin Cancer Res. 1997 Nov;3(11):1931-41.
4
Carcinomas of the colon and rectum. A comparison of staging classifications.结肠和直肠癌。分期分类比较。
Am Surg. 1986 Aug;52(8):428-33.
5
[Study of Dukes' staging of colorectal carcinoma by the prognosis. National Cooperative Group on Pathology and Prognosis of Colorectal Cancer].[结直肠癌Dukes分期与预后的研究。全国结直肠癌病理与预后协作组]
Zhonghua Zhong Liu Za Zhi. 1986 Mar;8(2):144-5.
6
Immunohistochemically detected thymidylate synthase in colorectal cancer: an independent prognostic factor of survival.免疫组织化学法检测结直肠癌中的胸苷酸合成酶:生存的独立预后因素
Clin Cancer Res. 2000 Feb;6(2):488-92.
7
[Pathologic findings in colorectal cancers and discussion of their significance for tumor therapy according to stage].
Wien Klin Wochenschr. 1987 Jul 17;99(14):488-93.
8
Delay of treatment is associated with advanced stage of rectal cancer but not of colon cancer.治疗延迟与直肠癌的晚期阶段相关,但与结肠癌无关。
Cancer Detect Prev. 2006;30(4):341-6. doi: 10.1016/j.cdp.2006.07.001. Epub 2006 Sep 11.
9
CEA as a prognostic factor in colorectal cancer.癌胚抗原作为结直肠癌的一个预后因素。
Anticancer Res. 1994 Mar-Apr;14(2B):705-8.
10
Staging of carcinoma of the colon and rectum.
Surg Gynecol Obstet. 1980 Jul;151(1):93-5.

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