de Prost Y, Bodemer C
Service de Dermatologie, Hôpital Necker, Paris.
Ann Med Interne (Paris). 1990;141(3):250-2.
Neonatal lupus erythematosus is characterized by congenital atrioventricular heart block and/or transient lupus skin lesions frequently similar to those seen in patients with subacute cutaneous lupus erythematosus. The mothers have anti-SSA (Ro) and/or anti-SSB (La) antibodies. The syndrome is important to recognize because newborns may develop complete heart block with congestive heart failure. However, in the majority of cases, neonatal lupus erythematosus is a relatively benign disorder and cutaneous lesions generally disappear completely by 6 months of age.
新生儿红斑狼疮的特征是先天性房室传导阻滞和/或短暂性狼疮皮肤病变,常类似于亚急性皮肤型红斑狼疮患者所见的病变。母亲具有抗SSA(Ro)和/或抗SSB(La)抗体。认识这种综合征很重要,因为新生儿可能会发展为伴有充血性心力衰竭的完全性心脏传导阻滞。然而,在大多数情况下,新生儿红斑狼疮是一种相对良性的疾病,皮肤病变通常在6个月大时完全消失。