Palmieri M, Gotti G, Zilio G, Chiozza R, Moratti P, Della Mea M T, Magris R
Service de Cardiologie et Unité de Soins Intensifs Coronaires, Hôpital Prov., Monfalcone, Italie.
Ann Cardiol Angeiol (Paris). 1990 Apr;39(4):195-8.
In order to improve the evaluation of the site and extent of the necrosis in acute myocardial infarction without Q wave (IMNQ), we used a multiparametric method taking into account the enzymatic values of the total CK, a score derived from Frank's VCG and a kinetic score of the VG segments estimated by echo-2D. The literature data have shown, according to the clinical and anatomical correlations, the frequency of the transmural lesions in the IMNQ cases and, on the contrary, of the lesions limited to the endocardial region and partially transmural in infarctions with new pathological Q waves. The heterogeneousness of the anatomo-pathological data can be explained by the mechanisms of the ischaemia, the site of the coronary occlusion, the presence or not of a spasm, the compensation by the collateral flux and eventually the effects of a treatment by fibrinolytic drugs.
为了改善对无Q波急性心肌梗死(IMNQ)坏死部位及范围的评估,我们采用了一种多参数方法,该方法考虑了总肌酸激酶(CK)的酶学值、从Frank心向量图(VCG)得出的评分以及通过二维超声心动图估计的心室节段动力学评分。文献数据根据临床与解剖学的相关性显示了IMNQ病例透壁性病变的频率,相反,在有新病理性Q波的梗死中,病变局限于心内膜区域及部分透壁性病变的频率。解剖病理数据的异质性可由缺血机制、冠状动脉闭塞部位、是否存在痉挛、侧支循环的代偿作用以及最终纤溶药物治疗的效果来解释。