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[心肌梗死后室性心动过速患者晚期电位的起源]

[The origin of late potentials in patients with ventricular tachycardia after myocardial infarction].

作者信息

Savard P, Lacroix D, Shenasa M, Kaltenbrunner W, Cardinal R, Pagé P, Joly D, Derome D, Nadeau R

机构信息

Hôpital du Sacré-Coeur, Montreal, Québec, Canada.

出版信息

Ann Cardiol Angeiol (Paris). 1990 May;39(5):275-9.

PMID:2369064
Abstract

In order to study the origin of late potentials, their distribution was analyzed in 16 patients who had undergone surgery for arrhythmia due to ventricular tachycardia following myocardial infarction. The potentials were measured in sinus rhythm using 63 unipolar leads placed on the chest before the operation, then on the epicardium and endocardium during the operation. Epicardial and/or endocardial activity extending beyond the QRS complex measured from unfiltered chest signals and characterized by slowed propagation at the edge or inside of necrotic regions, stable from one beat to the next, and showing simple (39 per cent), double (34 per cent) or fragmented (27 per cent) deflections on the electrocardiograms were observed in 5/6 patients without bundle-branch block and in 5/10 patients with block. Similar activity but which did not extend after the QRS was detected in the 6 other patients. For signals filtered at 55 Hz, a close correlation between the distribution of chest, epicardial and endocardial potentials was observed, thus allowing approximate location of the origin of late potentials from the chest. Anterior or apical sites corresponded to close extrema in the precordial region, whereas the other sites were associated with more distant extrema. An analysis of potential distribution thus gives a better understanding of the electrogenesis of late potentials as well as their detection on the chest.

摘要

为研究延迟电位的起源,对16例因心肌梗死后室性心动过速接受心律失常手术的患者的延迟电位分布进行了分析。术前在胸部放置63个单极导联,在窦性心律下测量电位,然后在手术期间在心外膜和心内膜测量。在5/6无束支传导阻滞的患者和5/10有束支传导阻滞的患者中,观察到心外膜和/或心内膜活动超出从未滤波的胸部信号测量的QRS波群,其特征为在坏死区域边缘或内部传导减慢,逐搏稳定,并且在心电图上显示简单(39%)、双重(34%)或碎裂(27%)的偏转。在其他6例患者中检测到类似活动,但在QRS波群后未延长。对于在55Hz滤波的信号,观察到胸部、心外膜和心内膜电位分布之间密切相关,从而允许从胸部大致定位延迟电位的起源。前部或心尖部位对应于胸前区的近端极值,而其他部位与更远的极值相关。因此,对电位分布的分析可以更好地理解延迟电位的电发生及其在胸部的检测。

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