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巴西里约热内卢精神药物使用的流行病学情况:精神疾病治疗方面的差距。

Epidemiology of psychotropic drug use in Rio de Janeiro, Brazil: gaps in mental illness treatments.

机构信息

Federal University of São Paulo - Paulista Medical School, São Paulo, Brazil.

出版信息

PLoS One. 2013 May 14;8(5):e62270. doi: 10.1371/journal.pone.0062270. Print 2013.

Abstract

OBJECTIVE

Estimate the prevalence of psychotropic drugs use in the city of Rio de Janeiro, Brazil, and establish its relationship with the presence of mental disorders.

METHODS

A probabilistic sample of non-institutionalized individuals, from the general population of Rio de Janeiro (n = 1208;turn out:81%), 15 years or older, who were interviewed using the Composite International Diagnostic Interview 2.1 (depression, anxiety-phobia, OCD\PTSD, alcoholism sections), and asked about their psychotropic use during a 12 and one-month period before the interview. Data were collected between June/2007-February/2008.The prevalence was estimated with a confidence interval of 95%. The associations between psychotropics use and mental disorders were analyzed through a logistic regression model (Odds Ration - OR).

RESULTS

The one-month prevalence of psychotropic drug use was 6.55%, 3.19% for men and 9.13% for women. Antidepressants were the most frequently used drug (2.78%), followed by anorectics (1.65%), tranquilizers (1.61%) and mood stabilizers (1.23%). General practitioners issued the highest number of prescriptions (46.3%), followed by psychiatrists (29.3%); 86.6% of the psychotropic drugs used were paid for by the patient himself. Individuals with increased likelihood of using psychotropic drugs were those that had received a psychiatric diagnosis during a one-month period before the study (OR:3.93), females (OR:1.82), separated/divorced (OR:2.23), of increased age (OR:1.03), with higher income (OR:2.96), and family history of mental disorder (OR:2.59); only 16% of the individuals with a current DSM IV diagnosis were using a psychotropic drug; 17% among individuals with a depression-related diagnosis and 8% with Phobic Anxiety Disorders-related diagnosis used psychotropics.

CONCLUSION

Approximately 84% of individuals displaying some mental disorder did not use psychotropic drugs, which indicates an important gap between demand and access to treatment. A significant failure is evident in the health system for patients with mental disorders; this could be due to health workers' inability to recognize mental disorders among individuals.

摘要

目的

估计巴西里约热内卢市精神药物使用的流行率,并确定其与精神障碍存在的关系。

方法

采用概率抽样方法,对来自里约热内卢(n=1208;应答率:81%)的一般人群中 15 岁及以上的非住院个体进行调查,采用复合国际诊断访谈 2.1(抑郁、焦虑-恐惧症、强迫症\创伤后应激障碍、酗酒部分)进行访谈,并询问他们在访谈前 12 个月和一个月内的精神药物使用情况。数据收集于 2007 年 6 月至 2008 年 2 月期间。采用 95%置信区间估计流行率。使用逻辑回归模型(优势比 - OR)分析精神药物使用与精神障碍之间的关系。

结果

一个月的精神药物使用流行率为 6.55%,男性为 3.19%,女性为 9.13%。抗抑郁药是最常用的药物(2.78%),其次是食欲抑制剂(1.65%)、镇静剂(1.61%)和情绪稳定剂(1.23%)。全科医生开出的处方最多(46.3%),其次是精神科医生(29.3%);86.6%的精神药物由患者自费购买。使用精神药物的可能性增加的个体是在研究前一个月内接受过精神科诊断的个体(OR:3.93)、女性(OR:1.82)、离异(OR:2.23)、年龄较大(OR:1.03)、收入较高(OR:2.96)和有精神障碍家族史(OR:2.59);只有 16%的目前 DSM-IV 诊断个体正在使用精神药物;17%的抑郁相关诊断个体和 8%的恐惧症相关焦虑障碍个体使用精神药物。

结论

大约 84%的有某种精神障碍的个体未使用精神药物,这表明需求与治疗之间存在重要差距。精神障碍患者的卫生系统明显存在失败,这可能是由于卫生工作者无法识别个体的精神障碍。

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