School of Biological Sciences, National Institute of Science Education and Research (NISER), Sachivalaya Marg, Odisha, India.
PLoS One. 2013 May 15;8(5):e63044. doi: 10.1371/journal.pone.0063044. Print 2013.
Stress has long been known to increase susceptibility to health disorders. In 2009, American Psychological Association further established association of stress to serious health problems. However, a quantitative and accurate way to evaluate and estimate stress status of individuals is still a big challenge. It has been shown, in large animal models using cattle, that psychological stress can be quantified as well as disease susceptibility could be predicted through biomarker discovery. Taking cue from those studies, we have evaluated and estimated psychological stress level of individuals theoretically and validated experimentally. Various biomarkers have also been identified which can be associated to psychological stress to predict stress status of unknown individuals.
压力一直被认为会增加健康失调的易感性。2009 年，美国心理协会进一步确定了压力与严重健康问题之间的关联。然而，评估和估计个体的压力状况的定量和准确方法仍然是一个巨大的挑战。已经表明，在使用牛的大型动物模型中，可以通过生物标志物的发现来量化心理压力，以及预测疾病易感性。从这些研究中得到启示，我们从理论上评估和估计了个体的心理压力水平，并通过实验进行了验证。还确定了各种与心理压力相关的生物标志物，以预测未知个体的压力状况。
