Institute for Infectious Disease and Endemic Disease Prevention and Control, Beijing Center for Disease Prevention and Control, Beijing, China.
PLoS One. 2013 May 14;8(5):e63668. doi: 10.1371/journal.pone.0063668. Print 2013.
To investigate the risk factors of scrub typhus infection in Beijing, China, a case-control study was carried out. Cases (n = 56) were defined as persons who were diagnosed by PCR and serological method within three years. Three neighborhood control subjects were selected by matching for age and occupation. Living at the edge of the village, living in the houses near grassland, vegetable field or ditch, house yard without cement floor, piling weeds in the house or yard, all of these were risk factors for scrub typhus infection. Working in vegetable fields and hilly areas, and harvesting in autumn posed the highest risks, with odds ratios (ORs) and 95% confidence intervals (CIs) of 3.7 (1.1-11.9), 8.2 (1.4-49.5), and 17.2 (5.1-57.9), respectively. These results would be useful for the establishment of a detail control strategy for scrub typhus infection in Beijing, China.
为了研究中国北京恙虫病感染的危险因素，开展了一项病例对照研究。病例（n=56）定义为在三年内通过 PCR 和血清学方法诊断的患者。通过年龄和职业匹配选择了 3 名邻里对照。居住在村庄边缘、居住在草地、菜地或沟渠附近的房屋、房屋院子没有水泥地面、房屋或院子里杂草丛生，这些都是恙虫病感染的危险因素。在菜地和山区工作，以及在秋季收获，感染风险最高，比值比（OR）和 95%置信区间（CI）分别为 3.7（1.1-11.9）、8.2（1.4-49.5）和 17.2（5.1-57.9）。这些结果将有助于在中国北京制定详细的恙虫病感染控制策略。
