Gao Jingjing, Zhang Xiansheng, Su Puyu, Liu Jishuang, Shi Kai, Hao Zongyao, Zhou Jun, Liang Chaozhao
Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
J Sex Med. 2013 Aug;10(8):1935-42. doi: 10.1111/jsm.12207. Epub 2013 May 20.
Although infertility is known to be associated with psychological and sexual problems, the relationship between these two aspects in infertile men has not been well investigated.
To investigate the incidence of sexual dysfunction and psychological burden, and their possible associations in infertile men.
From June 2009 to June 2012, a total of 1,468 infertile men and 942 fertile men were evaluated. Premature ejaculation (PE) and erectile dysfunction (ED) were measured by the PE diagnostic tool (PEDT), the intravaginal ejaculatory latency time (IELT) and the international index of erectile function (IIEF)-5. Anxiety and depression, which reflect the degree of psychological burden, were measured by the self-rating anxiety scale (SAS) and self-rating depression scale (SDS), respectively.
PE and ED were measured by the PEDT, IELT, and IIEF-5. Anxiety and depression were measured by the SAS and SDS, respectively.
The incidences of PE and ED in the infertile group were significantly higher than those in the fertile group (PE: 19.01% vs.10.93%, P < 0.001; ED: 18.05% vs. 8.28%, P < 0.001). In addition, anxiety and depression were more prevalent in infertile than fertile men (Anxiety: 38.01% vs. 26.65%, P < 0.001; Depression: 15.74% vs. 10.08%, P < 0.001). Furthermore, after adjusting for age in the infertile group, the PEDT score was positively associated with anxiety (adjusted r = 0.57; P < 0.001) and depression (adjusted r = 0.54; P < 0.001). Moreover, the IELT were negatively associated with anxiety (adjusted r = -0.40; P < 0.001) and depression (adjusted r = -0.52; P < 0.001). Similar negative relationships were also observed between the IIEF-5 score and anxiety (adjusted r = -0.49; P < 0.001) or depression (adjusted r = -0.50; P < 0.001).
This is the first study to systematically evaluate the incidence of sexual dysfunction and psychological burden, and their possible associations in infertile men in China. Further in-depth studies are needed to confirm and extend these results.
尽管已知不孕症与心理和性问题有关，但不育男性这两个方面之间的关系尚未得到充分研究。
调查性功能障碍和心理负担的发生率及其在不育男性中的可能关联。
2009年6月至2012年6月，共评估了1468名不育男性和942名生育能力正常的男性。早泄（PE）和勃起功能障碍（ED）通过早泄诊断工具（PEDT）、阴道内射精潜伏期（IELT）和国际勃起功能指数（IIEF-5）进行测量。反映心理负担程度的焦虑和抑郁分别通过自评焦虑量表（SAS）和自评抑郁量表（SDS）进行测量。
通过PEDT、IELT和IIEF-5测量PE和ED。分别通过SAS和SDS测量焦虑和抑郁。
不育组中PE和ED的发生率显著高于生育能力正常组（PE：19.01%对10.93%，P<0.001；ED：18.05%对8.28%，P<0.001）。此外，不育男性的焦虑和抑郁比生育能力正常的男性更普遍（焦虑：38.01%对26.65%，P<0.001；抑郁：15.74%对10.08%，P<0.001）。此外，在不育组中调整年龄后，PEDT评分与焦虑呈正相关（调整r=0.57；P<0.001）和抑郁呈正相关（调整r=0.54；P<0.001）。此外，IELT与焦虑呈负相关（调整r=-0.40；P<0.001）和抑郁呈负相关（调整r=-0.52；P<0.001）。在IIEF-5评分与焦虑（调整r=-0.49；P<0.001）或抑郁（调整r=-0.50；P<0.001）之间也观察到类似的负相关关系。
这是中国第一项系统评估性功能障碍和心理负担的发生率及其在不育男性中可能关联的研究。需要进一步深入研究以证实和扩展这些结果。
