Agre J C, Rodriquez A A
Department of Rehabilitation Medicine, University of Wisconsin-Madison Medical School 53792.
Arch Phys Med Rehabil. 1990 Jul;71(8):545-51.
The purpose of this study was to determine if there were any differences between symptomatic and asymptomatic polio survivors by history of acute poliomyelitis illness, electromyographic evidence of terminal motor unit reorganization, and neuromuscular function of the quadriceps femoris muscle. Thirty-four symptomatic postpolio subjects, 16 asymptomatic postpolio subjects, and 41 controls were studied. A questionnaire assessed polio history. Peak knee extension torque was measured isokinetically and isometrically. Endurance (time to exhaustion) was measured at 40% of maximal isometric torque. Work capacity was determined as the product of torque and duration. Recovery of isometric strength was measured at regular intervals for ten minutes after exhaustion. Quantitative electromyography was also performed on the quadriceps to determine motor unit action potential duration and amplitude. It was found that symptomatic subjects had evidence of more severe original polio involvement by history (documented electromyographically), were weaker and capable of performing less work than asymptomatic subjects, and recovered strength less readily than controls.
本研究的目的是通过急性脊髓灰质炎病史、终末运动单位重组的肌电图证据以及股四头肌的神经肌肉功能，来确定有症状和无症状的脊髓灰质炎幸存者之间是否存在差异。研究了34名有症状的脊髓灰质炎后受试者、16名无症状的脊髓灰质炎后受试者和41名对照者。通过问卷调查评估脊髓灰质炎病史。等速和等长测量膝关节伸展峰值扭矩。在最大等长扭矩的40% 时测量耐力（疲劳时间）。工作能力确定为扭矩与持续时间的乘积。在疲劳后十分钟内定期测量等长力量的恢复情况。还对股四头肌进行了定量肌电图检查，以确定运动单位动作电位的持续时间和幅度。结果发现，有症状的受试者根据病史（肌电图记录）显示出更严重的原始脊髓灰质炎受累情况，比无症状的受试者更虚弱，工作能力更低，而且力量恢复比对照者更慢。
